Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MAGED1 Antikörper (AA 20-224)

MAGED1 Reaktivität: Human WB Wirt: Maus Monoclonal 1305CT862-157-127 unconjugated
Produktnummer ABIN1944790
  • Target Alle MAGED1 Antikörper anzeigen
    MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
    Bindungsspezifität
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-224
    Reaktivität
    • 40
    • 15
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 33
    • 6
    • 1
    Maus
    Klonalität
    • 36
    • 4
    Monoklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAGED1 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1.
    Klon
    1305CT862-157-127
    Isotyp
    IgG1 kappa
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Wen, Xue, Qin, Yu, Zhang, Zhao, Gao, Gu, Li: "hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation." in: FEBS letters, Vol. 564, Issue 1-2, pp. 171-6, (2004) (PubMed).

    Salehi, Roux, Kubu, Zeindler, Bhakar, Tannis, Verdi, Barker: "NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis." in: Neuron, Vol. 27, Issue 2, pp. 279-88, (2000) (PubMed).

    Põld, Zhou, Chen, Hall, Vescio, Berenson: "Identification of a new, unorthodox member of the MAGE gene family." in: Genomics, Vol. 59, Issue 2, pp. 161-7, (1999) (PubMed).

  • Target
    MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
    Andere Bezeichnung
    MAGED1 (MAGED1 Produkte)
    Synonyme
    MAGED1 antikoerper, DLXIN-1 antikoerper, NRAGE antikoerper, 2810433C11Rik antikoerper, 5430405L04Rik antikoerper, DXBwg1492e antikoerper, Dlixin antikoerper, Dlxin-1 antikoerper, Dlxin1 antikoerper, MAGE-D1 antikoerper, mFLJ00163 antikoerper, Nrage antikoerper, MAGE family member D1 antikoerper, melanoma antigen family D, 1 antikoerper, melanoma antigen, family D, 1 antikoerper, MAGED1 antikoerper, Maged1 antikoerper
    Hintergrund
    Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
    Molekulargewicht
    86161
    Gen-ID
    9500
    UniProt
    Q9Y5V3
    Pathways
    Neurotrophin Signalübertragung
Sie sind hier:
Kundenservice