CHRNA9 Antikörper (N-Term)
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- Target Alle CHRNA9 Antikörper anzeigen
- CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))
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Bindungsspezifität
- AA 8-42, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHRNA9 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CHRNA9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 8-42 amino acids from the N-terminal region of human CHRNA9.
- Klon
- RB46802
- Isotyp
- Ig Fraction
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- Applikationshinweise
- WB: 1:1000. FC: 1:25
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).
: "Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytes." in: Life sciences, Vol. 76, Issue 3, pp. 263-80, (2004) (PubMed).
: "Chromosome location and characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) gene." in: Cytogenetic and genome research, Vol. 98, Issue 2-3, pp. 154-9, (2003) (PubMed).
: "A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit." in: Molecular pharmacology, Vol. 61, Issue 1, pp. 150-9, (2001) (PubMed).
: "Novel human alpha9 acetylcholine receptor regulating keratinocyte adhesion is targeted by Pemphigus vulgaris autoimmunity." in: The American journal of pathology, Vol. 157, Issue 4, pp. 1377-91, (2000) (PubMed).
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Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).
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- Target
- CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))
- Andere Bezeichnung
- CHRNA9 (CHRNA9 Produkte)
- Synonyme
- HSA243342 antikoerper, NACHRA9 antikoerper, 2410015I05Rik antikoerper, Acra9 antikoerper, EG666827 antikoerper, Gm8311 antikoerper, cholinergic receptor nicotinic alpha 9 subunit antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 9 antikoerper, CHRNA9 antikoerper, Chrna9 antikoerper
- Hintergrund
- Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion.
- Molekulargewicht
- 54807
- Gen-ID
- 55584
- UniProt
- Q9UGM1
- Pathways
- Sensory Perception of Sound
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