PLSCR1 Antikörper

Produktnummer ABIN192390

Produktdetails anti-PLSCR1 Antikörper

Target: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLSCR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Spezifität: The antibody 13A6 [TEC-23] binds to an intracellular epitope of rat Phospholipid Scramblase 1 (PLSCR1), an 37-49 kDa protein, accelerating bidirectional movement of plasma membrane phospholipids under conditions of elevated calcium.

Kreuzreaktivität (Details): Rat

Immunogen: Pooled lipid raft fraction isolated from RBL-2H3 cells

Klon: 13A6 [TEC-23]

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western blotting: Recommended dilution: 1 μg/mL, positive control: RBL (rat basophilic leukemia) cell line, both reducing and non-reducing conditions.
Flow cytometry: Intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilized with 15 mM sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.
Avoid prolonged exposure to light.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-PLSCR1 Antikörper (ABIN192390)

Smrz, Lebduska, Dráberová, Korb, Dráber: "Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10904-18, (2008) (PubMed).

Details zu PLSCR1

Target: PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Andere Bezeichnung: PLSCR1 (PLSCR1 Produkte)

Synonyme: mmtra1b antikoerper, MGC84969 antikoerper, PLSCR1 antikoerper, MGC148322 antikoerper, MMTRA1B antikoerper, MmTRA1a antikoerper, MmTRA1b antikoerper, Nor1 antikoerper, Tra1 antikoerper, Tra1a antikoerper, Tra1b antikoerper, Tras1 antikoerper, Tras2 antikoerper, PLSCR2 antikoerper, phospholipid scramblase 1 L homeolog antikoerper, phospholipid scramblase 1 antikoerper, plscr1.L antikoerper, PLS1 antikoerper, PVX_111580 antikoerper, PLSCR1 antikoerper, plscr1 antikoerper, Plscr1 antikoerper, LOC100712949 antikoerper, PLSCR2 antikoerper, LOC100341366 antikoerper, LOC611500 antikoerper

Hintergrund: Phospholipid scramblase 1,PLSCR1 (phospholipid scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.,PL scramblase 1, phospholipid scramblase 1

Gen-ID: 117540

UniProt: P58195

Pathways: Cellular Response to Molecule of Bacterial Origin