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Antikörper
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anti-CD2 Molecule CD2 Biotin
CD2 Molecule (CD2) Antikörper (Biotin)
| Antigen |
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| Synonyme |
T11, SRBC, FLJ46032, CD2, MGC140284, CD2R, LFA2, OX34, LFA-2, OX-34, Ly37, Ly-37 |
| Klonalität |
Monoklonal (LT2) |
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Wirt
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Reaktivität
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Human (207), Maus (92), Ratte (Rattus) (61), Schwein (30), Pferd (19), Hund (15), Affe (13), Schaf (12), Pavian (10), Rind (Kuh) (10), Cynomolgus (10), Rhesusaffen (10), Ziege (1)
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Konjugat
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FITC (50), Biotin (44), PE (33), APC (8), RPE (8), PE,Cy5 (4), Cy5 (3), DY647 (3), PE/Cy5 (3), Pacific Blue (3), Alexa Fluor 488 (2), Alexa Flour 488 (1), Alexa Fluor 647 (1), Alexa Fluor 700 (1), Cy3 (1), Cy5.5 (1), Cy7 (1), Dyomics 647 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy7 (1), PE/Cy7 (1), RBITC (1), RPE,Cy5 (1)
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Applikation
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Durchflusszytometrie (FACS) (305), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (84), Immunpräzipitation (IP) (78), Immunhistochemie (Paraffinschnitte) (IHC (p)) (64), Western Blot (WB) (26), Funktionale Studien (Func) (24), Immunfluoreszenz (IF) (20), Immunhistochemie (IHC) (9), ELISA (7), Blockierende Antikörper (Inhibition) (5), ELISA (Detektionsantikörper) (5), Enzyme Immunoassay (EIA) (5), Immunzytochemie (ICC) (4), Zytotoxizitätstest (CyTox) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Kostimulation (1), Dot Blot (Dot) (1), Immunelektronenmikroskopie (EM) (1)
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| Produktnummer |
ABIN192382 |
| Menge |
0.1 mg (1 mg/ml) |
| Preis |
230,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferbar innerhalb von 3 bis 5 Werktagen |
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Weitere Bezeichnung
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CD2
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Immunogen
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Normal human blood lymphocytes.
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Isotyp
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IgG2a
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Klon
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LT2
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Beschreibung
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CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interactionwith CD58 stabilizes adhesion between T cells and antigen presenting or target cells.Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within thetwo-dimensional cell-cell interface to provide tight adhesion. Morover, T cell activationinduces increased CD2 expression and its lateral mobility, making easier contact betweenCD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites ofcell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reducesintestinal inflammation and helps to control infection.
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Spezifität
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The antibody LT2 reacts with CD2, a 50 kDa glycoprotein present on the human peripheralblood T lymphocytes and NK cells, also expressed by all thymocytes.HLDA VI, WS Code T 6T-008
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Applikationshinweise
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The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5 µg/ml. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
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Konzentration
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1 mg/ml
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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Lagerung
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Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
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Forschungsgebiet
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Stammzellen, Hämopoetische Vorläufer, Hämatopoetische Stammzellen, Adaptive Immunität, CD Antigene, Oberflächenrezeptoren der Immunzellen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Publikationen
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Gannon, Rhind, Suzui et al.: "beta-Endorphin and natural killer cell cytolytic activity during prolonged exercise. is there a connection?" in: The American journal of physiology, Vol. 275, Issue 6 Pt 2, pp. R1725-34, 1999 (PubMed).
Lin, Liu, Chen et al.: "CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features." in: Blood, Vol. 106, Issue 10, pp. 3567-74, 2005 (PubMed).
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Alternativen zu Antigen "CD2 Molecule (CD2)", Typ "Antikörper" finden
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Wirte
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Maus (244), Ratte (87), Kaninchen (30)
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Reaktivitäten
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Human (207), Maus (92), Ratte (Rattus) (61), Schwein (30), Pferd (19), Hund (15), Affe (13), Schaf (12), Pavian (10), Rind (Kuh) (10), Cynomolgus (10), Rhesusaffen (10), Ziege (1)
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Applikationen
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Durchflusszytometrie (FACS) (305), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (84), Immunpräzipitation (IP) (78), Immunhistochemie (Paraffinschnitte) (IHC (p)) (64), Western Blot (WB) (26), Funktionale Studien (Func) (24), Immunfluoreszenz (IF) (20), Immunhistochemie (IHC) (9), ELISA (7), Blockierende Antikörper (Inhibition) (5), ELISA (Detektionsantikörper) (5), Enzyme Immunoassay (EIA) (5), Immunzytochemie (ICC) (4), Zytotoxizitätstest (CyTox) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Kostimulation (1), Dot Blot (Dot) (1), Immunelektronenmikroskopie (EM) (1)
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Konjugate
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FITC (50), Biotin (44), PE (33), APC (8), RPE (8), PE,Cy5 (4), Cy5 (3), DY647 (3), PE/Cy5 (3), Pacific Blue (3), Alexa Fluor 488 (2), Alexa Flour 488 (1), Alexa Fluor 647 (1), Alexa Fluor 700 (1), Cy3 (1), Cy5.5 (1), Cy7 (1), Dyomics 647 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy7 (1), PE/Cy7 (1), RBITC (1), RPE,Cy5 (1)
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Alternativen 
