CD7 (CD7) Antikörper (Biotin)
| Antigen |
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| Synonyme |
GP40, TP41, Tp40, LEU-9 |
| Klonalität |
Monoklonal (MEM-186) |
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Wirt
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Reaktivität
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Konjugat
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FITC (24), Biotin (19), PE (15), APC (9), Cy5,PE (4), Alexa Fluor 488 (2), Alexa Fluor 700 (2), PE,Cy5 (2), RPE (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy5.5,PE (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), PE,Cy7 (1), Pacific Blue (1), PerCP (1), RBITC (1), RPE,Cy5 (1)
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Applikation
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Durchflusszytometrie (FACS) (139), Western Blot (WB) (35), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (25), Immunpräzipitation (IP) (25), Immunfluoreszenz (IF) (23), Immunhistochemie (IHC) (6), ELISA (5), Funktionale Studien (Func) (5), Immunzytochemie (ICC) (4), ELISA (Detektionsantikörper) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN192061 |
| Menge |
0.1 mg (1 mg/ml) |
| Preis |
230,00 € Zzgl. Versandkosten €40,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 3 bis 5 Werktagen |
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Weitere Bezeichnung
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CD7
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Immunogen
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Human acute myelogenous leukaemia cell line KG-1.
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Isotyp
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IgG1
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Klon
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MEM-186
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Beschreibung
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CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells,NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is alsoexpressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux inT lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase.CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligandof CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocytesignaling and cytokine release. In lung microvascular endothelial cells CD7 serves as anIgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.
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Spezifität
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The MEM-186 antibody reacts with CD7, a 40 kD type I transmembrane glycoproteinexpressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors,monocytes (weakly) and also on acute lymphocytic leukemia.HLDA VI, WS Code T 6T-015
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Applikationshinweise
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Biotinylated antibody is designed for indirect immunofluorescence analysis by FlowCytometry and for. Working concentrations should be determined by the investigator.
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Konzentration
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1 mg/ml
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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Lagerung
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Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
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Forschungsgebiet
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Immunologie, Adaptive Immunität, CD Antigene, Oberflächenrezeptoren der Immunzellen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "CD7 (CD7)", Typ "Antikörper" finden
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Wirte
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Maus (140), Kaninchen (44), Ratte (6)
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Reaktivitäten
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Human (185), Maus (20), Ratte (Rattus) (20), Rind (Kuh) (5), Pferd (5), Schwein (5), Kaninchen (5), Hund (4), Huhn (2), Schaf (2)
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Applikationen
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Durchflusszytometrie (FACS) (139), Western Blot (WB) (35), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (27), Immunhistochemie (Paraffinschnitte) (IHC (p)) (25), Immunpräzipitation (IP) (25), Immunfluoreszenz (IF) (23), Immunhistochemie (IHC) (6), ELISA (5), Funktionale Studien (Func) (5), Immunzytochemie (ICC) (4), ELISA (Detektionsantikörper) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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FITC (24), Biotin (19), PE (15), APC (9), Cy5,PE (4), Alexa Fluor 488 (2), Alexa Fluor 700 (2), PE,Cy5 (2), RPE (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy5.5,PE (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), PE,Cy7 (1), Pacific Blue (1), PerCP (1), RBITC (1), RPE,Cy5 (1)
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Alternativen 
