Matrix Gla Protein (MGP) (AA 3-15) Antikörper

Antigen: Matrix Gla Protein (MGP)

Synonyme: NTI, GIG36, MGLAP, Mglap, MGP, mgp-A, LOC100136434, DKFZp468D0810, mgp

Epitope: AA 3-15

Klonalität: Monoklonal (52-1#1)

Wirt: Maus

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN191942

Produktbeschreibung

Produktmerkmale: Synonyms: MGP, MGLAP, GIG36

Weitere Bezeichnung: Matrix Gla Protein

Swiss-Prot: P08493

Immunogen: Synthetic human Matrix Gla Protein (aa 3-15)AA Sequence: SHESMESYELNPF

Kreuzreaktivität: Human

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 52-1#1

Beschreibung: MGP belongs to the osteocalcin/matrix Gla protein family and contains one Gla(gamma-carboxy-glutamate) domain. It associates with the organic matrix of bone andcartilage and is thought to act as an inhibitor of bone formation. Defects in MGP are the cause of Keutel syndrome (KS) [MIM: 245150]. KS is an autosomalrecessive disorder characterized by abnormal cartilage calcification, peripheral pulmonarystenosis neural hearing loss and midfacial hypoplasia.

Spezifität: This antibody detects matrix Gla protein carboxylated and non-carboxylated. Species: Human. Others not tested. Add. Information: Locus ID 4256

Anwendungen

Applikationshinweise: Immunohistochemistry on frozen sections (25 ug/ml). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Reinigung: Purified

Lagerung: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar