Bone sialoprotein 2 (native) Antikörper

Antigen: Bone sialoprotein 2 (native)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunfluoreszenz (IF), Immunhistochemie (Paraffinschnitte) (IHC (p)), Radioimmunoassay (RIA), Western Blot (WB)

Produktnummer: ABIN191810

Produktbeschreibung

Produktmerkmale: Synonyms: Bone sialoprotein II, BSP II, IBSP, BNSP, Cell-binding sialoprotein, Integrin-bindingsialoprotein

Swiss-Prot: P21815

Immunogen: Human Bone Sialoprotein (bone extract)

Format: Serum

Beschreibung: The protein encoded by the Bone Sialoprotein gene is a major structural protein of thebone matrix. It is synthesized by skeletal-associated cell types, including hypertrophicchondrocytes, osteoblasts, osteocytes, and osteoclasts, and it constitutes approximately12% of the noncollagenous proteins in human bone. The only extraskeletal site of itssynthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidicamino acid clusters, and mediates cell attachment through an RGD sequence thatrecognizes the vitronectin receptor.

Spezifität: This antibody detects Bone Sialoprotein, Bone Sialoprotein. There were no cross reactivities obtained with Human Osteonectin and HumanOsteopontin. Species: Human and Rat. Others not tested. Add. Information: LocusID 3381

Anwendungen

Applikationshinweise: RIA. ELISA. Western blot. Immunocytochemistry (1/100). Immunohistochemistry on Paraffin Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Lagerung: Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar