Low Density Lipoprotein (LDL) Cu2+ oxidized Antikörper

Antigen: Low Density Lipoprotein (LDL) Cu2+ oxidized

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunhistochemie (Gefrierschnitte) (IHC (fro))

Produktnummer: ABIN191766

Produktbeschreibung

Immunogen: human Cu2+-oxidized LDL

Kreuzreaktivität: Human, Maus

Beschreibung: LDL (low-density lipoprotein) is a type of lipoprotein that transports cholesterol andtriglycerides from the liver to peripheral tissues. LDL enables fats and cholesterol to movewithin the water based solution of the blood stream. LDL also regulates cholesterolsynthesis at these sites.

Spezifität: The antiserum shows strong reactivity to fully oxidized modifications of LDL including Cu2+-oxidized LDL, MDA-LDL, HOCL-LDL, but not to other oxidized proteins like MDA-HSA,MDA-HDL, HOCL-HSA, HOCL-HDL (below detection limit). The reaction to native LDL wasweak, but clearly detectable (approx. 20%). Minimally oxidized LDL gave a strong bindingsignal(> 80%). Species: Human. Others not tested.

Anwendungen

Applikationshinweise: ELISA and related methods (1: 500 - 1: 5.000). Immunohistochemistry on paraffin sections (< 1: 500). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Reinigung: Serum

Lagerung: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar