Cyclic GMP (cGMP) Antikörper

Antigen: Cyclic GMP (cGMP)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Radioimmunoassay (RIA)

Produktnummer: ABIN191762

Produktbeschreibung

Produktmerkmale: Synonyms: cGMP, cyclic guanosine monophosphate

Weitere Bezeichnung: Cyclic GMP

Immunogen: Synthetic human cGMP, poly Lysin conjugated

Kreuzreaktivität: Human

Beschreibung: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a mannersimilar to that observed with cAMP. Peptide hormones, such as the natriuretic factors,activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) alsostimulates cGMP production by activating soluble GC, perhaps by binding to the hememoiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effectsthrough the activation of specific cGMP dependent protein kinases (PKG).

Spezifität: This antibody detects Synthetic cGMP, no cross-reactivity with cAMP. Species: Human. Others not tested.

Anwendungen

Applikationshinweise: RIA (1: 800). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Reinigung: Serum

Lagerung: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar