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Epidermal Growth Factor Receptor (EGFR) Antikörper

Antigen

Epidermal Growth Factor Receptor (EGFR)
Synonyme
ERBB, HER1, mENA, ERBB1, PIG61, Wa5, wa2, Erbb, Errp, wa-2, AI552599, 9030024J15Rik, ErbB-1, C-erb, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DmHD-33,  ... mehr anzeigen
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Alternativen

Human
Applikation
Alternativen Enzyme Immunoassay (EIA), Western Blot (WB), Immunfluoreszenz (IF)
Produktnummer ABIN191749
Menge 20 µl  (Varianten)
Preis 110,00 €   Zzgl. Versandkosten €40,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung
Anwendungen Alternativen Sekundärantikörper Varianten zurück nach oben

Produktmerkmale Synonyms: Epidermal growth factor receptor, EGF Receptor, erbB-1, c-ErbB-1, Receptor tyrosine-proteinkinase erbB-1, Proto-oncogene c-ErbB-1
Weitere Bezeichnung EGFR / ERBB1
Swiss-Prot P00533
Immunogen Human native EGF-Receptor
Kreuzreaktivität Human
Beschreibung Protein kinases are enzymes that transfer a phosphate group from a phosphate donor ontoan acceptor amino acid in a substrate protein. By this basic mechanism, protein kinasesmediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism,transcription, cell cycle progression, cytoskeletal rearrangement and cell movement,apoptosis, and differentiation. The protein kinase family is one of the largest families ofproteins in eukaryotes, classified in 8 major groups based on sequence comparison oftheir tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growthfactor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of thehead and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary,esophagus, stomach and in squamous cell carcinoma.
Spezifität This antibody detects EGF-Receptor. Species: Human. Others not tested. Add. Information: LocusID 1956
Synonyme ERBB, HER1, mENA, ERBB1, PIG61, Wa5, wa2, Erbb, Errp, wa-2, AI552599, 9030024J15Rik, ErbB-1, C-erb, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DmHD-33, EFG-R, EGF-R, EGFR, EK2-6, Egf, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, HD-33, Torpedo/DER, Torpedo/Egfr, c-erbB, d-egf-r, dEGFR1, flb, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57EFa, l(2)57Ea, pnt, top, top/DER, top/flb, DmelCG10079, CG10079, egfr, EGFR12, EGFR15, egfr1, Erbb2

Anwendungen
Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise ELISA (1: 10.000). Immunflourescence (1: 1.000). Western blot (1: 500). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Reinigung Serum
Lagerung Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "Epidermal Growth Factor Receptor (EGFR)", Typ "Antikörper" finden
Wirte Kaninchen (472), Maus (193), Ratte (17), Schaf (13), Ziege (2), Huhn (1)
Reaktivitäten Human (670), Maus (285), Ratte (Rattus) (259), Hund (36), Schwein (19), Kaninchen (18), Huhn (9), Rind (Kuh) (6), Pferd (4), Schaf (2)
Applikationen Western Blot (WB) (484), Immunpräzipitation (IP) (162), Immunhistochemie (Paraffinschnitte) (IHC (p)) (159), Enzyme Immunoassay (EIA) (124), Immunfluoreszenz (IF) (118), Durchflusszytometrie (FACS) (107), Immunhistochemie (IHC) (105), ELISA (96), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (69), Dot Blot (Dot) (28), Blocking Antibody (Inhibition) (16), Immunzytochemie (ICC) (12), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), Funktionale Studien (Func) (3), ELISA (Detektionsantikörper) (2), Immunelektronenmikroskopie (EM) (2), Immunoelectron Microscopy (IEM) (2), Neutralisierung (Neut) (2), Blockierende Antikörper (Inhibition) (1), Radioimmunoassay (RIA) (1)
Konjugate Biotin (35), FITC (8), PE (5), Alexa Fluor 488 (3), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitope pTyr1197 (20), C-Term (17), pTyr869 (15), pTyr1092 (14), pThr678 (13), pTyr1172 (13), pTyr1110 (12), pSer1070 (11), pThr693 (11), AA 985-996 (5), N-Term (5), pTyr1016 (5), pTyr1068 (4), pTyr1069 (4), pTyr1173 (4), pSer695 (3), AA 1-203 (2), AA 1140-1160 (2), AA 960-980 (2), Extracell. non Ligand binding Site (2), S695 (2), Y1125 (2), Y869 (2), Y998 (2), pSer1026 (2), pSer1071 (2), pSer1166 (2), pSer1190 (2), pSer768 (2), pTyr1125 (2), pTyr845 (2), pTyr992 (2), pTyr998 (2), AA 1189-1199 (1), AA 25-140 (1), Ab-1016 (1), Ab-1026 (1), Ab-1069 (1), Ab-1071 (1), Amino Acids 1165-1186 (1), External Domain (1), Extracellular non-ligand binding site (1), S1026 (1), S1070 (1), S1071 (1), S1166 (1), S1190 (1), S991 (1), T678 (1), TYR1173 (1), Y1016 (1), Y1069 (1), Y1092 (1), Y1110 (1), Y1172 (1), Y978 (1), extracellular ligand binding site (1), internal (1), pS1070 (1), pS768 (1), pSer1070/1071 (1), pSer1142 (1), pSer967 (1), pTyr1086 (1), pTyr1101 (1), pTyr1148 (1), pTyr1173, pTyr1248 (1), pY1016 (1), pY1092 (1), pY1172 (1), prylated At Threonine 654 (1), prylated At Tyrosine 1045 (1), prylated At Tyrosine 1173 (1), prylated At Tyrosine 845 (1), prylated at Serine 1047 (1)

Varianten
Anwendungen Alternativen Sekundärantikörper zurück nach oben

Varianten