Natriuretic Peptide Receptor C/guanylate Cyclase C (Atrionatriuretic Peptide Receptor C) (NPR3) (AA 199-213) Antikörper

Antigen: Natriuretic Peptide Receptor C/guanylate Cyclase C (Atrionatriuretic Peptide Receptor C) (NPR3)

Synonyme: NPRC, ANPRC, GUCY2B, MGC158440, im:7138418, zgc:158440, si:dkey-199l1.2

Epitope: AA 199-213

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunfluoreszenz (IF)

Produktnummer: ABIN191695

Produktbeschreibung

Produktmerkmale: Synonyms: Atrial natriuretic peptide C-type receptor, ANP clearance receptor, ANP-C, NPR-C

Weitere Bezeichnung: NPR3 / ANPRC

Swiss-Prot: P17342

Immunogen: Synthetic human NPR-C (199-213) poly Lysin conjugatedAA Sequence: QEEGLHTSIYSFDET

Kreuzreaktivität: Human, Ratte (Rattus)

Beschreibung: The family of natriuretic peptides elicits a number of vascular, renal and endocrine effectsthat are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors inthe vasculature, kidney, adrenal and brain. Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to beat least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one(ANPC) which is probably responsible for the clearance of ANP from the circulation withouta role in signal transduction.

Spezifität: This antibody detects synthetic NPR-C (aa 199-213). Species: Human. Others not tested. Add. Information: LocusID 4883

Anwendungen

Applikationshinweise: Western blot (1: 1000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Reinigung: Serum

Lagerung: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar