This antibody detects Murine type VII Collagen (aa 757-967). Cross reacts with Human type VII Collagen. Not tested for reactivity with type VII Collagen from other species.
Aufreinigung
Protein G Chromatography
Immunogen
Recombinant Murine type VII Collagen (mixture of fragments aa 97-200, aa 479-578, aa 757-967) GST fusion protein. Genename: COL7A1
ELISA (1/5.000). Western blot (1/500). Immunocytochemistry on Frozen Sections (1/100). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore in aqua bidest to a concentration of 1 mg/mL.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store lyophilized at 2-8 °C and reconstituted at -20 °C.
COL7A1 antikoerper, collagen type VII alpha 1 chain antikoerper, collagen, type VII, alpha 1 antikoerper, COL7A1 antikoerper, col7a1 antikoerper
Hintergrund
Type VII Collagen fibrils are composed of three identical alpha collagen chains. It's location is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in the collagen V11 gene are associated with all forms of dystrophic epidermolysis bullosa.Synonyms: COL7A1, LC collagen, Long-chain collagen