Corticotropin Releasing Hormone Receptor 1 (CRHR1) (AA 250-263) Antikörper

Antigen: Corticotropin Releasing Hormone Receptor 1 (CRHR1)

Synonyme: CRF1, CRHR, CRF-R, CRFR1, CRHR1f, CRH-R1h, CRFR2, crhr2, CRF2, crhr2-A, Crhr, MGC124237, MGC124240, CRHR1, crhr1-A

Epitope: AA 250-263

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Maus

Applikation: ELISA, Immunfluoreszenz (IF), Immunhistochemie (IHC)

Produktnummer: ABIN190893

Produktbeschreibung

Weitere Bezeichnung: CRHR1 / CRF-R (aa 250 - 263)

Gen-ID: 1394, 12921 (mouse), 58959 (rat)

Immunogen: KLYYDNEKCWFGKR

Format: Affinity-purified

Beschreibung: All names and symbols: CRHR1, CRF-R, corticotropin releasing hormone receptor 1 , CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f , corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor. Official Symbol: CRHR1. RefSeq number(s): NP_004373.2

Spezifität: Human, Mouse, Rat, Dog, Cow, Sheep 415 aa

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Preliminary experiments in human colon, duodenum and placenta lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? This product is successfully used in immunofluoresence and immunohistochemistry on mouse brain.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Ungless, Singh, Crowder et al.: "Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons." in: Neuron, Vol. 39, Issue 3, pp. 401-7, 2003 (PubMed).