K(lysine) Acetyltransferase 6B (KAT6B) Antikörper

Antigen: K(lysine) Acetyltransferase 6B (KAT6B)

Synonyme: qkf, MORF, MOZ2, KAT6B, FLJ90335, KIAA0383, querkopf, DKFZp313G1618, id:ibd5103

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Rind (Kuh)

Applikation: Western Blot (WB), Immunhistochemie (IHC), Immunpräzipitation (IP)

Produktnummer: ABIN190695

Produktbeschreibung

Weitere Bezeichnung: Histone acetyltransferase (MYST4)

Immunogen: KLH-conjugated synthetic peptide chosen from a bovine histone acetyltrasferaseMYST4 A7E390

Format: Lyophilized

Beschreibung: MYST4 is a transcriptional coactivator with histone acetyltransferase activity. This protein is essential for normal mouse embryo development. Mouse mutants for MYST4 show craniofacial abnormalities, retards in post-natal development,defaults in the nevous system and neurogenique problems. Abnormal chromosomic rearengements of MYST4 with the CBP gene is involved in acutemyeloid leukaemia (AML)-M4. Furthermore, in the ovary and the testis of mammals, MYST4 is mainly localized in specialized cells involved in male and female gametogenesis.

Spezifität: Antibody will also react with bovine MYST4 isoforms (MORF and MORF ). Predicted reactivity: human.

Anwendungen

Applikationshinweise: Recommended Dilution 1:7500 with standard ECL (WB), 1:1000 (IHC). Additional Information: antibody has been used on extracts from bovine brain, thymus, muscle, lung,heart, liver, kidney and spleen .

Buffer: Affinity purified serum in PBS pH 7.4

Lagerung: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior toopening them to avoid any losses that might occur from lyophilized materialadhering to the cap or sides of the tubes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: McGraw, Morin, Vigneault et al.: "Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesis." in: BMC developmental biology, Vol. 7, pp. 123, 2008 (PubMed).