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F11 Receptor (CD321) (F11R) Antikörper
| Antigen | F11 Receptor (CD321) (F11R) |
| Synonyme | JAM, KAT, JAM1, JAMA, JCAM, CD321, JAM-1, JAM-A, PAM-1, wu:fc07c05, zgc:103642, F11R, jama.2 |
| Klonalität | Monoklonal (EP1042Y) |
| Wirt |
 Alternativen Kaninchen |
| Reaktivität |
Alternativen Human, Maus, Ratte (Rattus) |
| Applikation |
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Western Blot (WB)
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| Produktnummer | ABIN189475 |
| Menge | 0.1 ml |
| Preis | 400,00 € Zzgl. Versandkosten €40,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | CD321 / JAM1 |
| Gen-ID | 50848, 16456, 116479 |
| Swiss-Prot | Q9Y624 |
| Immunogen | Synthetic peptide corresponding to residues near the N-terminus of human JunctionalAdhesion Molecule 1. |
| Isotyp | IgG (Passende Sekundärantikörper) |
| Klon | EP1042Y |
| Beschreibung | Junctional Adhesion Molecules (JAMs) are components and regulators of thewell-characterized epithelial and endothelial tight junction. JAM is selectivelyconcentrated at intercellular junctions of endothelial and epithelial cells of differentorigins. Microscopy shows that JAM codistributes with tight junction components at theapical region of the intercellular cleft. A mAb directed to JAM (BV11) was found to inhibitspontaneous and chemokine-induced monocyte transmigration through an endothelialcell monolayer in vitro. Systemic treatment of mice with BV11 mAb blocked monocyteinfiltration upon chemokine administration in subcutaneous air pouches (1). The humanprotein shares a highly conserved structure and sequence with the murine protein.However it is distinct in that it is constitutively expressed on circulating neutrophils,monocytes, platelets and lymphocyte subsets (2). Alternate Names: anti-CD321 antibody, anti-CD 321 antibody, anti-CD321 antigen antibody, anti-F11receptor antibody, anti-F11R antibody, anti-JAM 1 antibody, anti-JAM A antibody,anti-JAM antibody, anti-JAM1 antibody, anti-JAMA antibody, anti-JCAM anti-antibody,anti-Junctional adhesion molecule A antibody, anti-KAT antibody, anti-PAM 1 antibody,anti-PAM1 antibody, anti-Platelet adhesion molecule 1 antibody, anti-Platelet adhesionmolecule antibody, anti-Platelet F11 receptor antibody, anti-UNQ264/PRO301 antibody. |
| Spezifität | A synthetic peptide corresponding to residues near the N-terminus of human JAM1 wasused as an immunogen. Species Reactivity: Reacts in human, mouse, and rat. Not tested in other species. |
Anwendungen
| Applikationshinweise | WB: 1:2000, IHC: 1:100 - 250 |
| Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. Preservative: 0.01% sodium azide. |
| Lagerung | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Forschungsgebiet | Zell-/Gewebemarker, CD Antigene, Oberflächenrezeptoren der Immunzellen |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Bilder
Alternativen
Alternativen zu Antigen "F11 Receptor (CD321) (F11R)", Typ "Antikörper" finden
| Wirte | Maus (13), Ratte (9), Kaninchen (2), Ziege (1) |
| Reaktivitäten | Human (16), Maus (11), Ratte (Rattus) (3), Hund (1), Schwein (1) |
| Applikationen | Durchflusszytometrie (FACS) (18), Immunpräzipitation (IP) (13), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (12), Western Blot (WB) (11), ELISA (Detektionsantikörper) (3), Enzyme Immunoassay (EIA) (3), Funktionale Studien (Func) (1), Immunhistochemie (Paraffinschnitte) (IHC (p)) (1) |
| Konjugate | Biotin (3) |
