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Antikörper
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anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (pTry207) Antik...
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (pTry207) Antikörper
| Antigen |
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| Synonyme |
Crkol, AA589403, AI325100, 1110025F07Rik, CRKL, MGC63469, zgc:63469, wu:fa55g05, wu:fj60e01 |
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Epitope
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| Klonalität |
Monoklonal (Y243) |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunfluoreszenz (IF), Western Blot (WB)
Western Blot (WB) (29), Immunhistochemie (IHC) (8), ELISA (7), Immunfluoreszenz (IF) (6), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), ELISA (Detektionsantikörper) (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Immunpräzipitation (IP) (3), Immunzytochemie (ICC) (2), Dot Blot (Dot) (1), Durchflusszytometrie (FACS) (1)
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| Produktnummer |
ABIN189273 |
| Menge |
0.1 ml |
| Preis |
400,00 € Zzgl. Versandkosten €40,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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CRKL
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Gen-ID
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1399, 12929, 287942
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Swiss-Prot
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P46109
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Isotyp
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IgG (Passende Sekundärantikörper)
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Klon
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Y243
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Beschreibung
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CrkL (Crk-like), a 36kDa protein predominantly expressed in hematopoietic cell lines, isa member of the Crk adapter protein family. Lacking any intrinsic enzymatic activity,CrkL is composed of one SH2 domain and two SH3 domains (1). The SH2 domain ofCrkL as been shown to interact with c-Cbl, Cas, Hef-1 and Paxillin (2), while theN-terminal SH3 can bind to c-ABL, Sos1 and C3G (3). Additionally, the phosphorylatedform of CrkL (pY207) binds to BCR-ABL oncogene in chronic myelogenous leukemiacells (4). Alternate Names: anti-Crk L antibody, anti-Crk like protein antibody, anti-Crkol antibody, anti-HGNC:2363antibody, anti-Oncogene CrkL antibody, anti-V crk avian sarcoma virus CT10 oncogenehomolog like antibody, anti-V crk sarcoma virus CT10 oncogene homolog avian likeantibody.
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Spezifität
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A synthetic peptide corresponding to residues in the SH2 domain, near the N-term ofhuman CrkL, was used as immunogen. Species Reactivity: Cross reacts in Human. Does not react in Mouse or Rat.
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Applikationshinweise
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Suggested working dilutions: immunohistochemistry 1:50-100,Western Blot 1:1000,Immunocytochemistry 1:50-100
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Buffer
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50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. Preservative: 0.01% sodium azide.
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Lagerung
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Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL)", Typ "Antikörper" finden
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Wirte
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Kaninchen (20), Ziege (7), Maus (6)
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Reaktivitäten
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Human (30), Maus (10), Ratte (Rattus) (8), Hund (1)
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Applikationen
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Western Blot (WB) (29), Immunhistochemie (IHC) (8), ELISA (7), Immunfluoreszenz (IF) (6), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), ELISA (Detektionsantikörper) (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Immunpräzipitation (IP) (3), Immunzytochemie (ICC) (2), Dot Blot (Dot) (1), Durchflusszytometrie (FACS) (1)
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Epitope
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pTry207 (22), pTyr207 (1)
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