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Activating Transcription Factor 2 (ATF2) Antikörper
| Antigen | Activating Transcription Factor 2 (ATF2) |
| Synonyme | HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420 |
| Klonalität | Monoklonal (E243) |
| Wirt |
Alternativen Kaninchen |
| Reaktivität |
Alternativen Human, Maus |
| Applikation |
Alternativen Immunfluoreszenz (IF), Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
|
| Produktnummer | ABIN189036 |
| Menge | 0.1 ml |
| Preis | 410,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Versandbereit innerhalb von 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | ATF2 |
| Gen-ID | 1386, 11909, 81647 |
| Swiss-Prot | P15336 |
| Isotyp | IgG (Passende Sekundärantikörper) |
| Klon | E243 |
| Beschreibung | ATF-2 (activating transcription factor-2, CRE-BP1) is a transcription factor that binds thecAMP response element (CRE) and AP-1 response element and is abundantlyexpressed in the brain. Various forms of cellular stress, including genotoxic agents,inflammatory cytokines, and UV irradiation, stimulate the transcriptional activity of ATF-2(2). SAPK and p38 MAPK can activate, in response to cellular stress, ATF-2 byphosphorylating this protein at Thr69 and Thr71. Mutations of these sites result in theloss of stress-induced transcription by ATF-2 (2-4). Alternate Names: anti-Activating Transcription Factor 2 antibody, anti-cAMP Response Element BindingProtein 2 antibody, anti-CRE BP1 antibody, anti-CREB 2 antibody, anti-CREB2antibody, anti-CREBP1 antibody, anti-HB 16 antibody, anti-HB16 antibody,anti-MGC111558 antibody, anti-mXBP antibody, anti-TREB 7 antibody, anti-TREB7antibody. |
| Spezifität | A synthetic peptide corresponding to residues in C-terminus of human ATF2 was usedas immunogen. The antibody does not cross-react with other ATF family members. Species Reactivity: Cross reacts with Human and Mouse. Does not react with Rat. |
Anwendungen
| Applikationshinweise | Suggested working dilutions: immunohistochemistry 1:250-1:500,immunoprecipitation 1:60,Western Blot 1:10000,Immunocytochemistry 1:250-1:500 |
| Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 00.5% BSA. Preservative: 0.01% sodium azide. |
| Lagerung | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Forschungsgebiet | Immunologie, Angeborene Immunität, Transkriptionsfaktoren |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
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