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Activating Transcription Factor 2 (ATF2) Antikörper

Antigen

Activating Transcription Factor 2 (ATF2)

Synonyme HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420
Klonalität Monoklonal (E242)
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunfluoreszenz (IF), Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Produktnummer ABIN189035
Menge 0.1 ml
Preis 410,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Versandbereit innerhalb von 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung ATF2
Gen-ID 1386, 11909, 81647
Swiss-Prot P15336
Isotyp IgG  (Passende Sekundärantikörper)
Klon E242
Beschreibung ATF-2 (activating transcription factor-2, CRE-BP1) is a transcription factor that binds thecAMP response element (CRE) and AP-1 response element and is abundantlyexpressed in the brain. Various forms of cellular stress, including genotoxic agents,inflammatory cytokines, and UV irradiation, stimulate the transcriptional activity of ATF-2(2). SAPK and p38 MAPK can activate, in response to cellular stress, ATF-2 byphosphorylating this protein at Thr69 and Thr71. Mutations of these sites result in theloss of stress-induced transcription by ATF-2 (2-4). Alternate Names: anti-Activating Transcription Factor 2 antibody, anti-cAMP Response Element BindingProtein 2 antibody, anti-CRE BP1 antibody, anti-CREB 2 antibody, anti-CREB2antibody, anti-CREBP1 antibody, anti-HB 16 antibody, anti-HB16 antibody,anti-MGC111558 antibody, anti-mXBP antibody, anti-TREB 7 antibody, anti-TREB7antibody.
Spezifität A synthetic peptide corresponding to residues N-terminus of human ATF-2 was used asimmunogen. The antibody does not cross-react with other ATF family members. Species Reactivity: Cross reacts with Human. Does not react with Mouse or Rat.

Anwendungen

Applikationshinweise Suggested working dilutions: immunohistochemistry 1:100,immunoprecipitation 1:50,Western Blot 1:10000,Immunocytochemistry 1:250 to 1:500
Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. Preservative: 0.01% sodium azide.
Lagerung Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Forschungsgebiet Immunologie, Angeborene Immunität, Transkriptionsfaktoren
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Activating Transcription Factor 2 (ATF2)", Typ "Antikörper" finden
Wirte Kaninchen (164), Maus (17), Ziege (5), Schaf (5)
Reaktivitäten Human (186), Maus (128), Ratte (Rattus) (113), Huhn (2), Xenopus laevis (2), Rind (Kuh) (1), Hund (1), Pferd (1)
Applikationen Western Blot (WB) (118), Immunhistochemie (IHC) (63), Immunhistochemie (Paraffinschnitte) (IHC (p)) (49), Immunfluoreszenz (IF) (38), Immunpräzipitation (IP) (38), Enzyme Immunoassay (EIA) (31), ELISA (24), Durchflusszytometrie (FACS) (14), Dot Blot (Dot) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunelektronenmikroskopie (EM) (1)
Konjugate Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pThr69/51 (7), pSer62/44 (6), pThr71/53 (6), Ab-112 or 94 (5), Ab-62 or 44 (5), Ab-69 or 51 (5), Ab-71 or 53 (5), Ab-73 or 55 (5), pSer112 or 94 (5), pSer62 or 44 (5), pThr69 or 51 (5), pThr71 or 53 (5), pThr73 or 55 (5), pSer112/94 (4), pThr73/55 (4), S44 (2), S94 (2), pThr71 (2), PSer340/322 (1), S322 (1), pSer44 (1), pSer472 (1), pSer490 + pSer498 (1), pSer94 (1), pThr51 (1), pThr69/51 + pThr71/53 (1), pThr79/51 (1)