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PRR5L Antikörper (Center)

PRR5L Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1887660
  • Target Alle PRR5L Antikörper anzeigen
    PRR5L (Proline Rich 5 Like (PRR5L))
    Bindungsspezifität
    • 1
    • 1
    • 1
    Center
    Reaktivität
    Human, Maus
    Wirt
    • 4
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 4
    Dieser PRR5L Antikörper ist unkonjugiert
    Applikation
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität (Details)
    At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid peptide near the center of human PRR5L.
    Top Product
    Discover our top product PRR5L Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Handhabung
    Avoid freezing and thawing repeatly.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • Target
    PRR5L (Proline Rich 5 Like (PRR5L))
    Andere Bezeichnung
    PRR5L (PRR5L Produkte)
    Synonyme
    PROTOR2 antikoerper, 2600010E01Rik antikoerper, 4833411O04Rik antikoerper, Protor-2 antikoerper, Protor2 antikoerper, RGD1309969 antikoerper, PRR5L antikoerper, FLJ14213 antikoerper, proline rich 5 like antikoerper, PRR5L antikoerper, Prr5l antikoerper, prr5l antikoerper
    Hintergrund
    Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2).PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2.Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.
    Synonyms: Proline-rich protein 5-like, Protor-2, PROTOR2
    NCBI Accession
    NP_001153639
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