Diacylglycerol O-Acyltransferase 1 (DGAT1) Antikörper

Antigen: Diacylglycerol O-Acyltransferase 1 (DGAT1)

Synonyme: DGAT, ARGP1, Dgat, C75990, D15Ertd23e, MGC139064, dgat1, zgc:77691, wu:fd36g11, DGAT1, ABX45, AS11, ATDGAT, DIACYLGLYCEROL ACYLTRANSFERASE, F27F23.24, RDS1, TAG1, TRIACYLGLYCEROL BIOSYNTHESIS DEFECT 1

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN188726

Produktbeschreibung

Weitere Bezeichnung: DGAT1

Gen-ID: 8694

Swiss-Prot: NP_0362111

Immunogen: Synthetic peptide, C-QNSMKPFKDMDYS, representing the internal region of the humanprotein according to NP_036211.1. Reference Sequence: NP_036211.1.

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: The enzyme encoded by this gene utilizes diacylglycerol and fatty acyl CoA assubstrates in order to catalyze the final stage of triacylglycerol synthesis. It is alsoinvolved in cellular as well as physiological metabolic processes. Alternate Names: anti-DGAT1 antibody, anti-DGAT1 antibody, anti-DGAT1 antibody, anti-diacylglycerolO-acyltransferase homolog 1 (mouse)antibody, anti-ARGP1 antibody,anti-DGATantibody, anti-ACAT related gene product 1 antibody, anti-acyl coenzymeA:cholesterol acyltransferase related gene 1 antibody, anti-diacylglycerolO-acyltransferase 1 antibody, anti-diglyceride acyltransferase antibody, anti-DGAT1antibody, anti-diacylglycerol O-acyltransferase homolog 1 (mouse) antibody,anti-ARGP1 antibody, anti-DGAT antibody, anti-ACAT related gene product 1 antibody,anti-acyl coenzyme A:cholesterol acyltransferase related gene 1 antibody,anti-diacylglycerol O-acyltransferase 1 antibody, anti-diglyceride acyltransferaseantibody.

Spezifität: Species Reactivity: Reacts with Human. Expected from sequence similarity: Mouse, rat and canine.

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 50kDaband observed in lysates of Human Duodenum (calculated MW of 55.3kDa according toNP_036211.1). Recommended concentration: 0.5-1ug/ml.

Konzentration: 0.5 mg/ml

Buffer: Tris-saline [ pH7.3] with 0.5% BSA. Preservative: 0.02% sodium azide.

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Forschungsgebiet: Krebs, Fettsäuren, Metabolismus

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western Blot: DGAT1 Antibody [ABIN188726] - ABIN188726 (0.5ug/ml) staining of Human Duodenum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publikationen

Publikationen: Bagnato, Igal: "Overexpression of diacylglycerol acyltransferase-1 reduces phospholipid synthesis, proliferation, and invasiveness in simian virus 40-transformed human lung fibroblasts." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52203-11, 2003 (PubMed).

Alsted, Nybo, Schweiger et al.: "Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training." in: American journal of physiology. Endocrinology and metabolism, Vol. 296, Issue 3, pp. E445-53, 2009 (PubMed).