Cholinergic Receptor, Muscarinic 1 (CHRM1) Antikörper

Antigen: Cholinergic Receptor, Muscarinic 1 (CHRM1)

Synonyme: M1, HM1, M1R, MGC30125, Chrm-1, mAChR, CHRM1, DKFZp459P0517

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN188571

Produktbeschreibung

Weitere Bezeichnung: Muscarinic acetylcholine receptor M1

Gen-ID: 1128

Swiss-Prot: NP_0007292

Immunogen: Synthetic peptide, CDKRRWRKIPKRPGSVH, representing the C Terminus of thehuman protein according to NP_000729.2. Reference Sequence: NP_000729.2.

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: The muscarinic cholinergic receptors belong to a larger family of G protein-coupledreceptors. The functional diversity of these receptors is defined by the binding ofacetylcholine and includes cellular responses such as adenylate cyclase inhibition,phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptorsinfluence many effects of acetylcholine in the central and peripheral nervous system.The muscarinic cholinergic receptor 1 is involved in mediation of vagally-inducedbronchoconstriction and in the acid secretion of the gastrointestinal tract. The geneencoding this receptor is localized to 11q13. Alternate Names: anti-CHRM1 antibody, anti-cholinergic receptor antibody, anti-muscarinic 1 antibody,anti-HM1 antibody, anti-M1 antibody, anti-MGC30125 antibody, anti-muscarinicacetylcholine receptor M1 antibody.

Spezifität: Species Reactivity: Reacts with Human. Expected from sequence similarity: Mouse, Rat and Canine.

Anwendungen

Applikationshinweise: Positive Controls: Human Brain lysate

Konzentration: 0.5 mg/ml

Buffer: Tris-saline [ pH7.3] with 0.5% BSA. Preservative: 0.02% sodium azide.

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Forschungsgebiet: Neurotransmitter , Hormone, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN188571 (1?g/ml) staining of Human Brain lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.