Cathepsin D Antikörper

Produktnummer ABIN1882228

Produktdetails anti-Cathepsin D Antikörper

Target: Cathepsin D (CTSD)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cathepsin D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged CTSD protein was used to produced this monoclonal antibody.

Klon: 892CT11-1-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Cathepsin D Antikörper (ABIN1882228)

Wu, Sun, Ma, Zhu, Zhang, Pan, Li, Liu, Diao, Li: "A C-terminally truncated mouse Best3 splice variant targets and alters the ion balance in lysosome-endosome hybrids and the endoplasmic reticulum." in: Scientific reports, Vol. 6, pp. 27332, (2018) (PubMed).

Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, (2011) (PubMed).

Redecker, Heckendorf, Grosch, Mersmann, Hasilik: "Molecular organization of the human cathepsin D gene." in: DNA and cell biology, Vol. 10, Issue 6, pp. 423-31, (1991) (PubMed).

Westley, May: "Oestrogen regulates cathepsin D mRNA levels in oestrogen responsive human breast cancer cells." in: Nucleic acids research, Vol. 15, Issue 9, pp. 3773-86, (1987) (PubMed).

Faust, Kornfeld, Chirgwin: "Cloning and sequence analysis of cDNA for human cathepsin D." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 15, pp. 4910-4, (1985) (PubMed).

Details zu Cathepsin D

Target: Cathepsin D (CTSD)

Andere Bezeichnung: CTSD (CTSD Produkte)

Synonyme: catD antikoerper, fb93e11 antikoerper, fj17b09 antikoerper, wu:fb93e11 antikoerper, wu:fj17b09 antikoerper, LOC398557 antikoerper, Cathd antikoerper, CatD antikoerper, LOC100136761 antikoerper, CTSD antikoerper, DKFZp469J0315 antikoerper, DDBDRAFT_0205785 antikoerper, DDBDRAFT_0215012 antikoerper, DDB_0205785 antikoerper, DDB_0215012 antikoerper, CLN10 antikoerper, CPSD antikoerper, CD antikoerper, cathepsin D antikoerper, cathepsin D S homeolog antikoerper, lysosomal aspartic protease antikoerper, cathepsin D-like antikoerper, ctsd antikoerper, LOC398557 antikoerper, ctsd.S antikoerper, CatD antikoerper, LOC5567565 antikoerper, LOC100136761 antikoerper, CTSD antikoerper, Cathd antikoerper, ctsD antikoerper, catd antikoerper, Ctsd antikoerper, LOC443060 antikoerper

Hintergrund: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Molekulargewicht: 44552

NCBI Accession: NP_001900

UniProt: P07339

Pathways: Peptide Hormone Metabolism