This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This SERPINA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the C-terminal region of human SERPINA3.
SERPINA3
Reaktivität: Maus, Ratte
WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Baumann, Huber, Bode, Grosse, Lesjak, Laurell: "Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins." in: Journal of molecular biology, Vol. 218, Issue 3, pp. 595-606, (1991) (PubMed).
Abraham, Shirahama, Potter: "Alpha 1-antichymotrypsin is associated solely with amyloid deposits containing the beta-protein. Amyloid and cell localization of alpha 1-antichymotrypsin." in: Neurobiology of aging, Vol. 11, Issue 2, pp. 123-9, (1990) (PubMed).
Target
SERPINA3
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
SERPINA3-1 antikoerper, Pi2 antikoerper, AACT antikoerper, ACT antikoerper, GIG25 antikoerper, A1AT antikoerper, PI antikoerper, alpha-1-PI antikoerper, AAT antikoerper, Pi antikoerper, Spi1 antikoerper, SERPINA3-5 antikoerper, serpina3 antikoerper, serpin A3-5 antikoerper, serpin family A member 3 antikoerper, alpha-1-antiproteinase F precursor antikoerper, serpin family A member 1 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog antikoerper, LOC396684 antikoerper, SERPINA3 antikoerper, LOC100008973 antikoerper, SERPINA1 antikoerper, Serpina1 antikoerper, SPIA5 antikoerper, serpina3.L antikoerper
Hintergrund
SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.