EIF3H Antikörper (C-Term)

Produktnummer ABIN1882076

Produktdetails anti-EIF3H Antikörper

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Bindungsspezifität: AA 234-263, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: B, C, X

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EIF3H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the C-terminal region of human EIF3H.

Klon: RB20154

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-EIF3H Antikörper (ABIN1882076)

Cappuzzo, Varella-Garcia, Rossi, Gajapathy, Valente, Drabkin, Gemmill: "MYC and EIF3H Coamplification significantly improve response and survival of non-small cell lung cancer patients (NSCLC) treated with gefitinib." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 4, Issue 4, pp. 472-8, (2009) (PubMed).

Details zu EIF3H

Target: EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))

Andere Bezeichnung: EIF3H (EIF3H Produkte)

Synonyme: EIF3S3 antikoerper, eIF3-gamma antikoerper, eIF3-p40 antikoerper, 1110008A16Rik antikoerper, 40kD antikoerper, 9430017H16Rik antikoerper, EIF3-P40 antikoerper, EIF3-gamma antikoerper, Eif3s3 antikoerper, eif3s3 antikoerper, eIF-3p40 antikoerper, En10 antikoerper, AO090038000435 antikoerper, EIF3H antikoerper, eIF3h antikoerper, BcDNA:GM14618 antikoerper, CG9124 antikoerper, Dmel\\CG9124 antikoerper, eIF-3 antikoerper, eIF3-S3 antikoerper, eIf3-p44 antikoerper, l(2)k09003 antikoerper, eIF3h-A antikoerper, eif3h antikoerper, fj02c04 antikoerper, wu:fj02c04 antikoerper, zgc:101085 antikoerper, eIF3h-B antikoerper, zgc:123049 antikoerper, eukaryotic translation initiation factor 3 subunit H antikoerper, eukaryotic translation initiation factor 3, subunit H antikoerper, eukaryotic translation initiation factor 3 subunit H S homeolog antikoerper, eukaryotic translation initiation factor 3 subunit H-like antikoerper, Eukaryotic initiation factor 3 p40 subunit antikoerper, eukaryotic translation initiation factor 3, subunit H, a antikoerper, Eukaryotic translation initiation factor 3 subunit H antikoerper, translation initiation factor eIF3h (p40) antikoerper, eukaryotic translation initiation factor 3, subunit H, b antikoerper, EIF3H antikoerper, Eif3h antikoerper, eif3h antikoerper, eif3h.S antikoerper, eIF3h antikoerper, AOR_1_722074 antikoerper, PAAG_02837 antikoerper, VDBG_01433 antikoerper, MGYG_06658 antikoerper, LOC100196680 antikoerper, eIF-3p40 antikoerper, eif3ha antikoerper, eif-3.H antikoerper, SPAC821.05 antikoerper, eif3hb antikoerper

Hintergrund: EIF3H is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Molekulargewicht: 39930

NCBI Accession: NP_003747

UniProt: O15372

Pathways: Ribonucleoprotein Complex Subunit Organization