PA2G4 Antikörper (C-Term)

Produktnummer ABIN1882075

Produktdetails anti-PA2G4 Antikörper

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Bindungsspezifität: AA 322-350, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PA2G4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human EBP1.

Klon: RB19220

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PA2G4 Antikörper (ABIN1882075)

Zhang, Linn, Liu, Melamed, Tavora, Young, Burger, Hamburger: "EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance." in: Molecular cancer therapeutics, Vol. 7, Issue 10, pp. 3176-86, (2008) (PubMed).

Details zu PA2G4

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Andere Bezeichnung: EBP1 (PA2G4 Produkte)

Synonyme: EBP1 antikoerper, HG4-1 antikoerper, p38-2G4 antikoerper, Ebp1 antikoerper, pa2g4 antikoerper, si:dz150i12.2 antikoerper, wu:fb19b11 antikoerper, wu:ft56d05 antikoerper, zgc:86732 antikoerper, ebp1 antikoerper, hg4-1 antikoerper, p38-2g4 antikoerper, pa2g4-a antikoerper, PA2G4 antikoerper, DKFZp469G2132 antikoerper, Pa2g4 antikoerper, MGC81621 antikoerper, 38kDa antikoerper, AA672939 antikoerper, Plfap antikoerper, proliferation-associated 2G4 antikoerper, proliferation-associated 2G4, a antikoerper, proliferation-associated 2G4, 38kDa antikoerper, proliferation-associated 2G4 L homeolog antikoerper, proliferation-associated protein 2G4 antikoerper, proliferation-associated 2G4 S homeolog antikoerper, proliferation-associated protein 2G4 pseudogene antikoerper, PA2G4 antikoerper, Pa2g4 antikoerper, pa2g4a antikoerper, pa2g4.L antikoerper, pa2g4 antikoerper, LOC100519773 antikoerper, pa2g4.S antikoerper, LOC693641 antikoerper

Hintergrund: PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.

Molekulargewicht: 43787

NCBI Accession: NP_006182

UniProt: Q9UQ80

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades