ZMPSTE24 Antikörper (C-Term)

Produktnummer ABIN1882012

Produktdetails anti-ZMPSTE24 Antikörper

Target: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Bindungsspezifität: AA 404-433, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZMPSTE24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-433 amino acids from the C-terminal region of human ZMPSTE24.

Klon: RB41841

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ZMPSTE24 Antikörper (ABIN1882012)

Fontaine-Bisson, Alessi, Saut, Fumeron, Marre, Dutour, Badens, Levy, Tichet, Juhan-Vague, Trégouët, Balkau, Morange: "Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 2, pp. 193-201, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Details zu ZMPSTE24

Target: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Andere Bezeichnung: ZMPSTE24 (Zmpste24 Produkte)

Synonyme: DDBDRAFT_0189115 antikoerper, DDBDRAFT_0237846 antikoerper, DDB_0189115 antikoerper, DDB_0237846 antikoerper, F2N1.21 antikoerper, F2N1_21 antikoerper, STE24 antikoerper, FACE-1 antikoerper, FACE1 antikoerper, HGPS antikoerper, PRO1 antikoerper, Ste24p antikoerper, A530043O15Rik antikoerper, D030046F19 antikoerper, Face-1 antikoerper, MADB antikoerper, fi45a02 antikoerper, wu:fi45a02 antikoerper, zgc:55655 antikoerper, zinc metallopeptidase STE24 antikoerper, zinc metallopeptidase STE24 L homeolog antikoerper, CAAX prenyl protease antikoerper, Peptidase family M48 family protein antikoerper, zinc metallopeptidase, STE24 antikoerper, zinc metallopeptidase, STE24 homolog antikoerper, ZMPSTE24 antikoerper, zmpste24.L antikoerper, zmpste24 antikoerper, ATSTE24 antikoerper, Zmpste24 antikoerper

Hintergrund: This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.

Molekulargewicht: 54813

NCBI Accession: NP_005848

UniProt: O75844