SMAD5 Antikörper (SMAD, Mothers Against DPP Homolog 5) (AA 241-269)

Details for Product anti-SMAD5 Antibody No. ABIN1881816, Anbieter: Anmelden zum Anzeigen
Antigen
  • SBN
  • fb67b04
  • mad
  • madh5
  • sb:cb400
  • smd5
  • wu:fb67b04
  • XSmad4alpha
  • dpc4
  • jip
  • jv5-1
  • madh4
  • smad10
  • smad5
  • xsmad4
  • DWFC
  • JV5-1
  • MADH5
  • 1110051M15Rik
  • AI451355
  • Dwf-C
  • Madh5
  • MusMLP
  • SMAD5
  • DKFZp468M0619
  • SMAD family member 5
  • MAD homolog 5 (Drosophila)
  • SMAD family member 4, gene 2
  • SMAD5
  • smad5
  • smad4.2-b
  • Smad5
Epitop
AA 241-269, Center
19
16
10
10
5
4
4
3
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human
105
47
38
8
7
6
6
5
5
4
3
2
2
1
Wirt
Kaninchen
67
39
1
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser SMAD5 Antikörper ist unkonjugiert
3
3
3
3
3
3
Applikation
Western Blotting (WB)
102
57
28
25
19
18
10
3
2
1
1
1
1
Optionen
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Immunogen This SMAD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human SMAD5.
Klon RB40948
Homologie Mouse (Murine),Rat (Rattus)
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Andere Bezeichnung SMAD5 (SMAD5 Antibody Abstract)
Hintergrund Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).

Synonyms: SMAD5, MADH5, Mothers against decapentaplegic homolog 5, JV5-1, SMAD family member 5
NCBI Accession NP_001001419, NP_005894, NP_001001420
UniProt Q99717
Forschungsgebiet Organogenesis, Signaling, Transcription Factors
Applikationshinweise WB: 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Bilder des Herstellers
Western Blotting (WB) image for anti-SMAD5 Antikörper (SMAD, Mothers Against DPP Homolog 5) (AA 241-269) (ABIN1881816) SMAD5 Antibody (Center) (ABIN1881816) pre-incubated without(lane 1) and with(lane 2) ...
Produkt verwendet in: Yang, Li, Al-Lamki, Southwood, Zhao, Lever, Grimminger, Schermuly, Morrell: "Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo." in: Circulation research, Vol. 107, Issue 2, pp. 252-62, 2010 (PubMed).

Tao, Sampath: "Alternative splicing of SMADs in differentiation and tissue homeostasis." in: Development, growth & differentiation, Vol. 52, Issue 4, pp. 335-42, 2010 (PubMed).

Park, Lee, Ahn, Kim: "Predicting the multi-modal binding propensity of small molecules: towards an understanding of drug promiscuity." in: Molecular bioSystems, Vol. 5, Issue 8, pp. 844-53, 2009 (PubMed).

Middlebrook, Eldin, Li, Shivasankaran, Pangas: "Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors." in: Endocrinology, Vol. 150, Issue 12, pp. 5208-17, 2009 (PubMed).

Su, Zhu, Han, Feng, Huang, Ren, Pan, Zhang, Lu, Huang: "BMP4-Smad signaling pathway mediates adriamycin-induced premature senescence in lung cancer cells." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12153-64, 2009 (PubMed).