SF3A2 Antikörper (AA 166-194)

Produktnummer ABIN1881795

Produktdetails anti-SF3A2 Antikörper

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Bindungsspezifität: AA 166-194

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SF3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human SF3A2.

Klon: RB42212

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-SF3A2 Antikörper (ABIN1881795)

Tanackovic, Krämer: "Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo." in: Molecular biology of the cell, Vol. 16, Issue 3, pp. 1366-77, (2005) (PubMed).

Takenaka, Nakagawa, Miyamoto, Miki: "The pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling protein." in: The Biochemical journal, Vol. 382, Issue Pt 1, pp. 223-30, (2004) (PubMed).

Details zu SF3A2

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Andere Bezeichnung: SF3A2 (SF3A2 Produkte)

Synonyme: SAP62 antikoerper, SF3a66 antikoerper, sf3a2 antikoerper, MGC52805 antikoerper, prp11 antikoerper, prpf11 antikoerper, sap62 antikoerper, sf3a66 antikoerper, SF3A2 antikoerper, 66kDa antikoerper, AW047242 antikoerper, PRP11 antikoerper, SFA66 antikoerper, Sap62 antikoerper, PRPF11 antikoerper, splicing factor 3a subunit 2 antikoerper, splicing factor 3a subunit 2 S homeolog antikoerper, splicing factor 3a, subunit 2 antikoerper, SF3A2 antikoerper, sf3a2.S antikoerper, sf3a2 antikoerper, Sf3a2 antikoerper

Hintergrund: This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.

Molekulargewicht: 49256

NCBI Accession: NP_009096

UniProt: Q15428

Pathways: Ribonucleoprotein Complex Subunit Organization