SCNN1B Antikörper (AA 306-332)

Produktnummer ABIN1881778

Produktdetails anti-SCNN1B Antikörper

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Bindungsspezifität: AA 306-332

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCNN1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SCNN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-332 amino acids from the Central region of human SCNN1B.

Klon: RB42043

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-SCNN1B Antikörper (ABIN1881778)

Song, Wei, Zhou, Lazrak, Liu, Londino, Squadrito, Matalon: "Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9716-28, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Azad, Rauh, Vermeulen, Jaspers, Korbmacher, Boissier, Bassinet, Fichou, des Georges, Stanke, De Boeck, Dupont, Balascáková, Hjelte, Lebecque: "Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease." in: Human mutation, Vol. 30, Issue 7, pp. 1093-103, (2009) (PubMed).

Details zu SCNN1B

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Andere Bezeichnung: SCNN1B (SCNN1B Produkte)

Synonyme: BESC1 antikoerper, ENaCb antikoerper, ENaCbeta antikoerper, SCNEB antikoerper, RNENACB antikoerper, besc1 antikoerper, betaxENaC antikoerper, enacb antikoerper, enacbeta antikoerper, scnn1b antikoerper, beta-ENaC antikoerper, scneb antikoerper, SCNN1B antikoerper, BETA-ENAC antikoerper, sodium channel epithelial 1 beta subunit antikoerper, sodium channel, non voltage gated 1 beta subunit L homeolog antikoerper, sodium channel, non voltage gated 1 beta subunit antikoerper, sodium channel, nonvoltage-gated 1 beta antikoerper, sodium channel, non voltage gated 1 beta subunit S homeolog antikoerper, SCNN1B antikoerper, Scnn1b antikoerper, scnn1b.L antikoerper, scnn1b antikoerper, scnn1b.S antikoerper

Hintergrund: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.

Molekulargewicht: 72659

NCBI Accession: NP_000327

UniProt: P51168