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CDKN1B Antikörper (pThr197)

CDKN1B Reaktivität: Maus DB Wirt: Kaninchen Polyclonal RB42131 unconjugated
Produktnummer ABIN1881619
  • Target Alle CDKN1B Antikörper anzeigen
    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
    Bindungsspezifität
    • 29
    • 28
    • 22
    • 19
    • 17
    • 16
    • 11
    • 10
    • 10
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr197
    Reaktivität
    • 278
    • 128
    • 108
    • 26
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 240
    • 52
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 231
    • 65
    Polyklonal
    Konjugat
    • 146
    • 24
    • 17
    • 16
    • 16
    • 14
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CDKN1B Antikörper ist unkonjugiert
    Applikation
    • 206
    • 134
    • 74
    • 62
    • 53
    • 40
    • 36
    • 26
    • 25
    • 16
    • 16
    • 13
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Dot Blot (DB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This mouse p27Kip1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T197 of mouse p27Kip1.
    Klon
    RB42131
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CDKN1B Primärantikörper
  • Applikationshinweise
    DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Singh, Jatzek, Plisch, Srinivasan, Svaren, Suresh: "Regulation of memory CD8 T-cell differentiation by cyclin-dependent kinase inhibitor p27Kip1." in: Molecular and cellular biology, Vol. 30, Issue 21, pp. 5145-59, (2010) (PubMed).

    Antico-Arciuch, Dima, Liao, Refetoff, Di Cristofano: "Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females." in: Oncogene, Vol. 29, Issue 42, pp. 5678-86, (2010) (PubMed).

    Mitsuhashi, Yonemoto, Sone, Kosuge, Kosaki, Takahashi: "In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 37, pp. 16331-5, (2010) (PubMed).

    Zhang, Li, Yuan, Tian, Weidenfeld, Yang, Liu, Chokas, Morrisey: "Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms." in: Genes & development, Vol. 24, Issue 16, pp. 1746-57, (2010) (PubMed).

    Wang, Li, Jiao, Zhang, Shao, Yuan, Yu: "RNA interference reveals a requirement for both p18INK4c and p27Kip1 in B lymphopoiesis." in: Journal of molecular cell biology, Vol. 2, Issue 4, pp. 209-16, (2010) (PubMed).

  • Target
    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
    Andere Bezeichnung
    p27Kip1 (CDKN1B Produkte)
    Synonyme
    CDKN4 antikoerper, KIP1 antikoerper, MEN1B antikoerper, MEN4 antikoerper, P27KIP1 antikoerper, cdkn1b antikoerper, sb:cb611 antikoerper, wu:fb63g10 antikoerper, wu:fb64g10 antikoerper, wu:fe18e03 antikoerper, CDKN1B antikoerper, Kip1 antikoerper, p27 antikoerper, FAM14D antikoerper, ISG12 antikoerper, ISG12A antikoerper, P27 antikoerper, Cdki1b antikoerper, AA408329 antikoerper, AI843786 antikoerper, p27Kip1 antikoerper, cdkn1bl antikoerper, cyclin dependent kinase inhibitor 1B antikoerper, cyclin-dependent kinase inhibitor 1Bb antikoerper, interferon alpha inducible protein 27 antikoerper, cyclin-dependent kinase inhibitor 1B antikoerper, cyclin-dependent kinase inhibitor 1Ba antikoerper, CDKN1B antikoerper, cdkn1bb antikoerper, IFI27 antikoerper, Cdkn1b antikoerper, cdkn1ba antikoerper
    Hintergrund
    This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].
    Molekulargewicht
    22193
    NCBI Accession
    NP_034005
    UniProt
    P46414
    Pathways
    Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagie
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