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KRT6A Antikörper (AA 212-240)

KRT6A Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB40714 unconjugated
Produktnummer ABIN1881486
  • Target Alle KRT6A Antikörper anzeigen
    KRT6A (Keratin 6A (KRT6A))
    Bindungsspezifität
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 212-240
    Reaktivität
    • 65
    • 20
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 60
    • 16
    • 1
    Kaninchen
    Klonalität
    • 58
    • 19
    Polyklonal
    Konjugat
    • 38
    • 12
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KRT6A Antikörper ist unkonjugiert
    Applikation
    • 56
    • 38
    • 26
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Krt6a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of mouse Krt6a.
    Klon
    RB40714
    Isotyp
    IgG
    Top Product
    Discover our top product KRT6A Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Sehic, Khuu, Risnes, Osmundsen et al.: "Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of..." in: European journal of oral sciences, Vol. 117, Issue 2, pp. 93-104, (2009) (PubMed).

    Chen, Jaeger, Den, Koch, Sundberg, Roop: "Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita." in: The Journal of investigative dermatology, Vol. 128, Issue 2, pp. 270-9, (2008) (PubMed).

    Cui, Kunisada, Esibizione, Grivennikov, Piao, Nedospasov, Schlessinger: "Lymphotoxin-beta regulates periderm differentiation during embryonic skin development." in: Human molecular genetics, Vol. 16, Issue 21, pp. 2583-90, (2007) (PubMed).

    Gu, Coulombe: "Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles." in: The Journal of investigative dermatology, Vol. 127, Issue 5, pp. 1061-73, (2007) (PubMed).

    Kurek, Garinis, van Doorninck, van der Wees, Grosveld: "Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles." in: Development (Cambridge, England), Vol. 134, Issue 2, pp. 261-72, (2006) (PubMed).

  • Target
    KRT6A (Keratin 6A (KRT6A))
    Andere Bezeichnung
    Krt6a (KRT6A Produkte)
    Synonyme
    CK6A antikoerper, CK6C antikoerper, CK6D antikoerper, K6A antikoerper, K6C antikoerper, K6D antikoerper, KRT6C antikoerper, KRT6D antikoerper, 2310016L08Rik antikoerper, Krt2-6a antikoerper, Krt2-6c antikoerper, MK6a antikoerper, mK6[a] antikoerper, CK-6A antikoerper, Krt6a antikoerper, KRT6A antikoerper, keratin 6A antikoerper, similar to keratin complex 2, basic, gene 6a antikoerper, keratin, type II cytoskeletal 6A antikoerper, KRT6A antikoerper, Krt6a antikoerper, LOC683313 antikoerper, LOC101112304 antikoerper
    Hintergrund
    Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77 % of all forms found in epithelia.
    Molekulargewicht
    59335
    NCBI Accession
    NP_032502
    UniProt
    P50446
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