ISCU Antikörper (C-Term)
-
- Target Alle ISCU Antikörper anzeigen
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
-
Bindungsspezifität
- AA 138-167, C-Term
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ISCU Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This ISCU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human ISCU.
- Klon
- RB35591
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ISCU Primärantikörper
-
-
- Applikationshinweise
- WB: 1:1000. WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
-
-
Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 12, pp. 4362-8, (2010) (PubMed).
: "MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2." in: Cell metabolism, Vol. 10, Issue 4, pp. 273-84, (2009) (PubMed).
: "Clinical manifestation and a new ISCU mutation in iron-sulphur cluster deficiency myopathy." in: Brain : a journal of neurology, Vol. 132, Issue Pt 8, pp. 2170-9, (2009) (PubMed).
: "Mapping iron binding sites on human frataxin: implications for cluster assembly on the ISU Fe-S cluster scaffold protein." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 13, Issue 5, pp. 825-36, (2008) (PubMed).
: "Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance." in: American journal of human genetics, Vol. 82, Issue 3, pp. 652-60, (2008) (PubMed).
: "
-
Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 12, pp. 4362-8, (2010) (PubMed).
-
- Target
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Andere Bezeichnung
- ISCU (ISCU Produkte)
- Synonyme
- nifun antikoerper, zC191D15.3 antikoerper, si:ch211-191d15.3 antikoerper, 2310020H20Rik antikoerper, HML antikoerper, ISU2 antikoerper, NIFU antikoerper, NIFUN antikoerper, hnifU antikoerper, RGD1309562 antikoerper, AA407971 antikoerper, Nifu antikoerper, Nifun antikoerper, iron-sulfur cluster assembly enzyme ISCU, mitochondrial antikoerper, iron-sulfur cluster assembly enzyme antikoerper, iron-sulfur cluster assembly enzyme a antikoerper, LOC409130 antikoerper, ISCU antikoerper, iscua antikoerper, Iscu antikoerper
- Hintergrund
- Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.
- Molekulargewicht
- 17999
- NCBI Accession
- NP_055116, NP_998760
- UniProt
- Q9H1K1
-