This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HOXC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-250 amino acids from the C-terminal region of human HOXC10.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Hwang, Seok, Song, Jo, Lee: "HOXC10 as a potential marker for discriminating between amnion- and decidua-derived mesenchymal stem cells." in: Cloning and stem cells, Vol. 11, Issue 2, pp. 269-79, (2009) (PubMed).
Zhai, Kuick, Nan, Ota, Weiss, Trimble, Fearon, Cho: "Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion." in: Cancer research, Vol. 67, Issue 21, pp. 10163-72, (2007) (PubMed).
Gabellini, Colaluca, Vodermaier, Biamonti, Giacca, Falaschi, Riva, Peverali: "Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression." in: The EMBO journal, Vol. 22, Issue 14, pp. 3715-24, (2003) (PubMed).
Kosaki, Kosaki, Suzuki, Yoshihashi, Takahashi, Sasaki, Tomita, McGinnis, Matsuo: "Complete mutation analysis panel of the 39 human HOX genes." in: Teratology, Vol. 65, Issue 2, pp. 50-62, (2002) (PubMed).
Sandrock, Egly: "A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH." in: The Journal of biological chemistry, Vol. 276, Issue 38, pp. 35328-33, (2001) (PubMed).
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.