Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

EGFR Antikörper (pSer768)

EGFR Reaktivität: Human WB, DB Wirt: Kaninchen Polyclonal RB11271 unconjugated
Produktnummer ABIN1881286
  • Target Alle EGFR Antikörper anzeigen
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Bindungsspezifität
    • 41
    • 39
    • 39
    • 38
    • 36
    • 28
    • 28
    • 27
    • 22
    • 21
    • 21
    • 19
    • 18
    • 17
    • 16
    • 16
    • 15
    • 15
    • 15
    • 14
    • 14
    • 13
    • 13
    • 11
    • 11
    • 11
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    pSer768
    Reaktivität
    • 833
    • 330
    • 322
    • 26
    • 26
    • 24
    • 21
    • 15
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 650
    • 186
    • 14
    • 11
    • 5
    • 1
    Kaninchen
    Klonalität
    • 598
    • 264
    • 2
    Polyklonal
    Konjugat
    • 434
    • 65
    • 33
    • 31
    • 31
    • 30
    • 29
    • 27
    • 27
    • 26
    • 24
    • 18
    • 10
    • 10
    • 10
    • 10
    • 10
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EGFR Antikörper ist unkonjugiert
    Applikation
    • 581
    • 264
    • 151
    • 149
    • 140
    • 103
    • 101
    • 96
    • 81
    • 55
    • 36
    • 34
    • 34
    • 19
    • 10
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Dot Blot (DB)
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This EGFR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S768 of human EGFR.
    Klon
    RB11271
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product EGFR Primärantikörper
  • Applikationshinweise
    WB: 1:1000. DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Aifa, Aydin, Nordvall, Lundström, Svensson, Hermanson: "A basic peptide within the juxtamembrane region is required for EGF receptor dimerization." in: Experimental cell research, Vol. 302, Issue 1, pp. 108-14, (2004) (PubMed).

    Adams, McKern, Ward: "Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor." in: Growth factors (Chur, Switzerland), Vol. 22, Issue 2, pp. 89-95, (2004) (PubMed).

    Ichinose, Murata, Yanagida, Sako: "EGF signalling amplification induced by dynamic clustering of EGFR." in: Biochemical and biophysical research communications, Vol. 324, Issue 3, pp. 1143-9, (2004) (PubMed).

    Kuribayashi, Kataoka, Kurabayashi, Miura: "Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells." in: Endocrinology, Vol. 145, Issue 11, pp. 4976-84, (2004) (PubMed).

    Kapoor, Zhan, Johnson, ORourke: "Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells." in: Molecular and cellular biology, Vol. 24, Issue 2, pp. 823-36, (2003) (PubMed).

  • Target
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Andere Bezeichnung
    EGFR (EGFR Produkte)
    Synonyme
    C-erb antikoerper, CG10079 antikoerper, D-EGFR antikoerper, D-Egf antikoerper, DEGFR antikoerper, DER antikoerper, DER flb antikoerper, DER/EGFR antikoerper, DER/faint little ball antikoerper, DER/top antikoerper, DER/torpedo antikoerper, DER1 antikoerper, DEgfr antikoerper, Degfr antikoerper, Der antikoerper, DmHD-33 antikoerper, Dmel\\CG10079 antikoerper, EFG-R antikoerper, EGF-R antikoerper, EGFR antikoerper, EGFr antikoerper, EGfr antikoerper, EK2-6 antikoerper, Egf antikoerper, Egf-r antikoerper, EgfR antikoerper, El antikoerper, Elp antikoerper, Elp-1 antikoerper, Elp-B1 antikoerper, Elp-B1RB1 antikoerper, HD-33 antikoerper, TOP antikoerper, Torpedo/DER antikoerper, Torpedo/Egfr antikoerper, c-erbB antikoerper, d-egf-r antikoerper, dEGFR antikoerper, dEGFR1 antikoerper, dEgfr antikoerper, der antikoerper, egfr antikoerper, flb antikoerper, l(2)05351 antikoerper, l(2)09261 antikoerper, l(2)57DEFa antikoerper, l(2)57EFa antikoerper, l(2)57Ea antikoerper, mor1 antikoerper, top antikoerper, top/DER antikoerper, top/flb antikoerper, torpedo/Egfr antikoerper, torpedo/egfr antikoerper, EGFR12 antikoerper, EGFR15 antikoerper, egfr1 antikoerper, Erbb2 antikoerper, ERBB antikoerper, ERBB1 antikoerper, HER1 antikoerper, PIG61 antikoerper, mENA antikoerper, ErbB-1 antikoerper, Errp antikoerper, 9030024J15Rik antikoerper, AI552599 antikoerper, Erbb antikoerper, Errb1 antikoerper, Wa5 antikoerper, wa-2 antikoerper, wa2 antikoerper, epidermal growth factor receptor antikoerper, Epidermal growth factor receptor antikoerper, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) antikoerper, EGFR antikoerper, Egfr antikoerper, egfra antikoerper, egfr1 antikoerper, LOC5564544 antikoerper
    Hintergrund
    Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. It is involved in the control of cell growth and differentiation
    Molekulargewicht
    134277
    NCBI Accession
    NP_005219, NP_958439, NP_958440, NP_958441
    UniProt
    P00533
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
Sie sind hier:
Kundenservice