RCAS1 Antikörper (AA 88-117)

Produktnummer ABIN1881276

Produktdetails anti-RCAS1 Antikörper

Target: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Bindungsspezifität: AA 88-117

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EBAG9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human EBAG9.

Klon: RB41813

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-RCAS1 Antikörper (ABIN1881276)

Wolf, Reimer, Schuck, Rüder, Gerlach, Müller, Otto, Dörken, Rehm: "Role of EBAG9 protein in coat protein complex I-dependent glycoprotein maturation and secretion processes in tumor cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 4000-19, (2010) (PubMed).

Sonoda, Miyamoto, Nakashima, Wake: "Receptor-binding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding." in: Experimental cell research, Vol. 316, Issue 11, pp. 1795-803, (2010) (PubMed).

Ali-Fehmi, Chatterjee, Ionan, Levin, Arabi, Bandyopadhyay, Shah, Bryant, Hewitt, ORand, Alekseev, Morris, Munkarah, Abrams, Tainsky: "Analysis of the expression of human tumor antigens in ovarian cancer tissues." in: Cancer biomarkers : section A of Disease markers, Vol. 6, Issue 1, pp. 33-48, (2010) (PubMed).

Yang, Zhao, Liao, Zhang, Hu, Dai: "[Evaluation of RCAS1 as serum tumor marker for pancreatic cancer]." in: Zhonghua wai ke za zhi [Chinese journal of surgery], Vol. 47, Issue 13, pp. 999-1001, (2009) (PubMed).

Adamek, Radwańska, Gajda: "Expression of RCAS1 protein in microglia/macrophages accompanying brain tumours. An immunofluorescence study." in: Folia neuropathologica, Vol. 47, Issue 3, pp. 240-6, (2009) (PubMed).

Details zu RCAS1

Target: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Andere Bezeichnung: EBAG9 (EBAG9 Produkte)

Synonyme: EB9 antikoerper, PDAF antikoerper, MGC56608 antikoerper, zgc:56608 antikoerper, MGC84425 antikoerper, EBAG9 antikoerper, AI835379 antikoerper, Rcas1 antikoerper, RCAS1 antikoerper, eb9 antikoerper, pdaf antikoerper, rcas1 antikoerper, estrogen receptor binding site associated, antigen, 9 antikoerper, estrogen receptor binding site associated, antigen, 9 L homeolog antikoerper, estrogen receptor-binding fragment-associated gene 9 antikoerper, EBAG9 antikoerper, ebag9 antikoerper, ebag9.L antikoerper, Ebag9 antikoerper

Hintergrund: This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.

Molekulargewicht: 24377

NCBI Accession: NP_001265867, NP_004206, NP_936056

UniProt: O00559