DAB2 Antikörper (C-Term)

Produktnummer ABIN1881248

Produktdetails anti-DAB2 Antikörper

Target: DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))

Bindungsspezifität: AA 624-650, C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Dab2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-650 amino acids from the C-terminal region of mouse Dab2.

Klon: RB40861

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-DAB2 Antikörper (ABIN1881248)

Collaco, Jakab, Hegan, Mooseker, Ameen: "Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 17177-87, (2010) (PubMed).

Chaudhury, Hussey, Ray, Jin, Fox, Howe: "TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI." in: Nature cell biology, Vol. 12, Issue 3, pp. 286-93, (2010) (PubMed).

Hasumi, Baba, Ajima, Hasumi, Valera, Klein, Haines, Merino, Hong, Yamaguchi, Schmidt, Linehan: "Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 44, pp. 18722-7, (2009) (PubMed).

Jain, Nguyen, Friedline, Malhotra, Brehm, Koyanagi, Bix, Cooper, Chambers, Kang: "Cutting edge: Dab2 is a FOXP3 target gene required for regulatory T cell function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 7, pp. 4192-6, (2009) (PubMed).

Jiang, Luo, Howe: "Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions." in: Oncogene, Vol. 28, Issue 33, pp. 2999-3007, (2009) (PubMed).

Details zu DAB2

Target: DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))

Andere Bezeichnung: Dab2 (DAB2 Produkte)

Synonyme: DOC-2 antikoerper, DOC2 antikoerper, 5730435J12Rik antikoerper, AA960054 antikoerper, AI957090 antikoerper, D15Wsu122e antikoerper, D630005B22Rik antikoerper, Doc-2 antikoerper, Doc2 antikoerper, p96 antikoerper, DAB2, clathrin adaptor protein antikoerper, disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) antikoerper, Dab, mitogen-responsive phosphoprotein, homolog 2 antikoerper, disabled 2, mitogen-responsive phosphoprotein antikoerper, DAB2 antikoerper, dab2 antikoerper, Dab2 antikoerper

Hintergrund: Component of the CSF-1 signal transduction pathway.

Molekulargewicht: 82312

NCBI Accession: NP_001008702, NP_001032994, NP_075607

UniProt: P98078

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process