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Cyclin B2 Antikörper (pSer22)

CCNB2 Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB42147 unconjugated
Produktnummer ABIN1881157
  • Target Alle Cyclin B2 (CCNB2) Antikörper anzeigen
    Cyclin B2 (CCNB2)
    Bindungsspezifität
    • 15
    • 14
    • 14
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer22
    Reaktivität
    • 87
    • 31
    • 14
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 96
    • 5
    • 3
    Kaninchen
    Klonalität
    • 88
    • 16
    Polyklonal
    Konjugat
    • 44
    • 10
    • 10
    • 9
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cyclin B2 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 48
    • 43
    • 14
    • 13
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Dot Blot (DB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CCNB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S22 of human CCNB2.
    Klon
    RB42147
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CCNB2 Primärantikörper
  • Applikationshinweise
    DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Haraguchi, Ishikawa, Yamaguchi, Fujisawa: "Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia." in: Fertility and sterility, Vol. 91, Issue 4 Suppl, pp. 1424-6, (2009) (PubMed).

    De Martino, Visone, Wierinckx, Palmieri, Ferraro, Cappabianca, Chiappetta, Forzati, Lombardi, Colao, Trouillas, Fedele, Fusco: "HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas." in: Cancer research, Vol. 69, Issue 5, pp. 1844-50, (2009) (PubMed).

    Cunningham, Vierkant, Sellers, Phelan, Rider, Liebow, Schildkraut, Berchuck, Couch, Wang, Fridley, Gentry-Maharaj, Menon, Hogdall, Kjaer, Whittemore, DiCioccio, Song, Gayther, Ramus, Pharaoh, Goode: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." in: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).

    Bellanger, de Gramont, Sobczak-Thépot: "Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2." in: Oncogene, Vol. 26, Issue 51, pp. 7175-84, (2007) (PubMed).

    Stav, Bar, Sandbank: "Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma." in: The International journal of biological markers, Vol. 22, Issue 2, pp. 108-13, (2007) (PubMed).

  • Target
    Cyclin B2 (CCNB2)
    Andere Bezeichnung
    CCNB2 (CCNB2 Produkte)
    Synonyme
    HsT17299 antikoerper, CycB2 antikoerper, sb:cb303 antikoerper, cycB2 antikoerper, LOC100136691 antikoerper, C-B2 antikoerper, cyclinb2 antikoerper, hst17299 antikoerper, LOC100282653 antikoerper, cyclin B2 antikoerper, cyclin B2 S homeolog antikoerper, CCNB2 antikoerper, Ccnb2 antikoerper, ccnb2 antikoerper, LOC100136691 antikoerper, LOC100282653 antikoerper, ccnb2.S antikoerper
    Hintergrund
    Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
    Molekulargewicht
    45282
    NCBI Accession
    NP_004692
    UniProt
    O95067
    Pathways
    Zellzyklus, M Phase
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