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ATP1A3 Antikörper (AA 805-833)

ATP1A3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB42176 unconjugated
Produktnummer ABIN1881087
  • Target Alle ATP1A3 Antikörper anzeigen
    ATP1A3 (ATPase, Na+/K+ Transporting, alpha 3 Polypeptide (ATP1A3))
    Bindungsspezifität
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 805-833
    Reaktivität
    • 25
    • 11
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 24
    • 3
    Kaninchen
    Klonalität
    • 24
    • 3
    Polyklonal
    Konjugat
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATP1A3 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    C, M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ATP1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-833 amino acids from the Central region of human ATP1A3.
    Klon
    RB42176
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Einholm, Toustrup-Jensen, Holm, Andersen, Vilsen: "The rapid-onset dystonia parkinsonism mutation D923N of the Na+, K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site." in: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 26245-54, (2010) (PubMed).

    Floyd, Wray, Quenby, Martín-Vasallo, Mobasheri: "Expression and distribution of Na, K-ATPase isoforms in the human uterus." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 17, Issue 4, pp. 366-76, (2010) (PubMed).

    Goldstein, Lerer, Laiba, Mallet, Mujaheed, Laurent, Rosen, Ebstein, Lichtstein: "Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders." in: Biological psychiatry, Vol. 65, Issue 11, pp. 985-91, (2009) (PubMed).

  • Target
    ATP1A3 (ATPase, Na+/K+ Transporting, alpha 3 Polypeptide (ATP1A3))
    Andere Bezeichnung
    ATP1A3 (ATP1A3 Produkte)
    Synonyme
    AHC2 antikoerper, DYT12 antikoerper, RDP antikoerper, Atpa-2 antikoerper, Atpa1a3 antikoerper, ATPa1a3 antikoerper, atp[a]3A antikoerper, cb706 antikoerper, fj35g11 antikoerper, wu:fj35g11 antikoerper, wu:fq14g09 antikoerper, atp[a]3B antikoerper, cb705 antikoerper, wu:fj56a06 antikoerper, ATPase Na+/K+ transporting subunit alpha 3 antikoerper, ATPase, Na+/K+ transporting, alpha 3 polypeptide antikoerper, ATPase, Na+/K+ transporting, alpha 3 polypeptide L homeolog antikoerper, ATPase, Na+/K+ transporting, alpha 3b polypeptide antikoerper, ATPase, Na+/K+ transporting, alpha 3a polypeptide antikoerper, ATP1A3 antikoerper, Atp1a3 antikoerper, atp1a3.L antikoerper, atp1a3b antikoerper, atp1a3a antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit.
    Molekulargewicht
    111749
    NCBI Accession
    NP_001243142, NP_001243143, NP_689509
    UniProt
    P13637
    Pathways
    Thyroid Hormone Synthesis, Proton Transport, Ribonucleoside Biosynthetic Process
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