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ATG4B Antikörper (AA 250-290)

ATG4B Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1881082
  • Target Alle ATG4B Antikörper anzeigen
    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
    Bindungsspezifität
    • 21
    • 18
    • 15
    • 13
    • 13
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-290
    Reaktivität
    • 116
    • 45
    • 28
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 114
    • 4
    Kaninchen
    Klonalität
    • 113
    • 5
    Polyklonal
    Konjugat
    • 51
    • 10
    • 9
    • 9
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATG4B Antikörper ist unkonjugiert
    Applikation
    • 98
    • 41
    • 27
    • 26
    • 23
    • 16
    • 13
    • 13
    • 11
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Homologie
    B, C, Zf, M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from the Central region of human ATG4B.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ATG4B Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Kabeya, Mizushima, Yamamoto, Oshitani-Okamoto, Ohsumi, Yoshimori: "LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation." in: Journal of cell science, Vol. 117, Issue Pt 13, pp. 2805-12, (2004) (PubMed).

  • Target
    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
    Andere Bezeichnung
    ATG4B (ATG4B Produkte)
    Hintergrund
    Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
    Molekulargewicht
    44294
    NCBI Accession
    NP_037457, NP_847896
    UniProt
    Q9Y4P1
    Pathways
    Autophagie
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