Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) Antikörper

Antigen: Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1)

Synonyme: SLAM, CD150, CDw150, SLAMF1, RGD1560634

Klonalität: Monoklonal (IPO-3)

Wirt: Maus

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Immunfluoreszenz (IF), Western Blot (WB)

Produktnummer: ABIN187612

Produktbeschreibung

Weitere Bezeichnung: CD150 / SLAMF1

Immunogen: Activated B cell line

Isotyp: IgG2a  (Passende Sekundärantikörper)

Klon: IPO-3

Beschreibung: SLAM (signaling lymphocyte activation molecule), also known as CDw150, is a transmembrane type I protein present on the surface of T and B cells, and is a self-ligand mediating T and B cell interactions. Absence of an inhibitor (SAP) which blocks recruitment of the signal transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region is associated with X-linked lymphoproliferative disease.

Spezifität: Binds human SLAM (CDw150) antigen. Species Reactivity: Human. Others not tested.

Anwendungen

Applikationshinweise: ELISA: Use at a 1:750 dilution. Flow cytometry: Use at a 1:750 dilution. Immunohistochemistry: (frozen sections) Use at a 1:75 dilution. The optimal dilution for a specific application should be determined by the researcher.

Buffer: 100 µL of 1 mg/mL (100 µg) monoclonal antibody in 1X PBS, pH 7.2 without sodium azide. Purified by Protein A chromatography.

Lagerung: Store at 4 °C short term, -20 °C or below long term. Aliquot to avoid freeze / thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Yoneda, Fujita, Sato et al.: "Reverse genetics of Nipah virus to probe viral pathogenicity." in: Methods in molecular biology (Clifton, N.J.), Vol. 515, pp. 329-37, 2009 (PubMed).