Desmoglein 3 Antikörper
-
- Target Alle Desmoglein 3 (DSG3) Antikörper anzeigen
- Desmoglein 3 (DSG3)
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Desmoglein 3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Reacts with the 140 kDa desmoglein 3 protein. Does not cross-react with desmoglein 1 or desmoglein 2. The antibody does not inhibit biological activity of desmoglein 3. Species Reactivity: Human. Others not tested.
- Sterilität
- 0.2 μm filtered
- Klon
- 5G11
- Isotyp
- IgG1
- Top Product
- Discover our top product DSG3 Primärantikörper
-
-
- Applikationshinweise
- Immunofluorescence: Use at a 1:10 dilution Immunohistochemistry (paraffin embedded sections) Immunoprecipitation Western blot: Use at a 1:10 dilution The optimal dilution for a specific application should be determined by the researcher.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- 1 mL at 100 µg/mL of 0.2 µm filtered antibody solution in PBS containing 0.1% protein stabilizer and 0.02% sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
-
- Target
- Desmoglein 3 (DSG3)
- Andere Bezeichnung
- Desmoglein-3 (DSG3 Produkte)
- Synonyme
- DSG3 antikoerper, CDHF6 antikoerper, PVA antikoerper, bal antikoerper, balding antikoerper, desmoglein 3 antikoerper, DSG3 antikoerper, Dsg3 antikoerper
- Hintergrund
- Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments.
-