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AIRE Antikörper (Internal Region)

Verified AIRE Reaktivität: Human, Schwein WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN185643
  • Target Alle AIRE Antikörper anzeigen
    AIRE (Autoimmune Regulator (AIRE))
    Bindungsspezifität
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 51
    • 23
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    Human, Schwein
    Wirt
    • 47
    • 6
    • 1
    Ziege
    Klonalität
    • 53
    Polyklonal
    Konjugat
    • 38
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AIRE Antikörper ist unkonjugiert
    Applikation
    • 39
    • 24
    • 19
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    AIRE
    Sequenz
    KDVDLSQPRK GRKP
    Kreuzreaktivität
    Rind (Kuh), Hund, Human, Ratte
    Aufreinigung
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Güteklasse
    Verified
    Immunogen
    Peptide with sequence C-KDVDLSQPRKGRKP, from the internal region of the protein sequence according to NP_000374.1.
    Isotyp
    IgG
    Top Product
    Discover our top product AIRE Primärantikörper
  • Applikationshinweise

    Immunohistochemistry: In paraffin embedded Human Thymus shows nuclear staining in select thymocytes. This antibody has been successfully used in IHC on Human: Ströbel P et al. (2014) PMID: 24236644. This antibody has been successfully used in IHC on Pig:

    Western Blot: Appr. 60 kDa in transfected HEK293 lysates (calculated MW of 57.7 kDa according to NP_000374.1). Recommended concentration: 0.5-1.0 μg/mL.

    Peptide ELISA: antibody detection limit dilution 1:32000.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Minimize freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Suzuki, Suzuki, Nakai, Sembon, Fuchimoto, Onishi: "Transcriptional and histological analyses of the thymic developmental process in the fetal pig." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 63, Issue 2, pp. 215-25, (2014) (PubMed).

    Ströbel, Hartmann, Rosenwald, Kalla, Ott, Friedel, Schalke, Kasahara, Tomaru, Marx: "Corticomedullary differentiation and maturational arrest in thymomas." in: Histopathology, Vol. 64, Issue 4, pp. 557-66, (2014) (PubMed).

  • Target
    AIRE (Autoimmune Regulator (AIRE))
    Andere Bezeichnung
    AIRE (AIRE Produkte)
    Synonyme
    AIRE1 antikoerper, APECED antikoerper, APS1 antikoerper, APSI antikoerper, PGA1 antikoerper, autoimmune regulator antikoerper, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antikoerper, AaeL_AAEL013794 antikoerper, CpipJ_CPIJ001208 antikoerper, CpipJ_CPIJ001209 antikoerper, AIRE antikoerper, Aire antikoerper
    Hintergrund
    AIRE, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) , AIRE1, APECED, APS1, APSI, PGA1 , autoimmune regulator (APECED protein), autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy),
    Gen-ID
    326
    NCBI Accession
    NP_000374
    Pathways
    Chromatin Binding
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