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AHI1 Antikörper (N-Term)

Verified AHI1 Reaktivität: Human ELISA, FACS Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN185303
  • Target Alle AHI1 Antikörper anzeigen
    AHI1 (Abelson Helper Integration Site 1 (AHI1))
    Bindungsspezifität
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 26
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 24
    • 5
    Ziege
    Klonalität
    • 26
    • 3
    Polyklonal
    Konjugat
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AHI1 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    AHI1 / Jouberin
    Sequenz
    PTAESEAKVK TC
    Homologie
    Human
    Aufreinigung
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Güteklasse
    Verified
    Immunogen
    Peptide with sequence PTAESEAKVKTC, from the N Terminus of the protein sequence according to NP_060121.3, NP_001128303.1, NP_001128302.1, NP_001128304.1.
    Isotyp
    IgG
    Top Product
    Discover our top product AHI1 Primärantikörper
  • Applikationshinweise

    DS WB Results: Preliminary experiments gave a consistent band at approx 75-80 kDa in Human Cerebellum and Frontal Cortex lysates after 0.5 μg/mL antibody staining and was successfully blocked by incubation with the immunizing peptide. Please note that currently we cannot find an explanation in the literature for this band, given the calculated size of 137 kDa according to NP_060121.3

    Peptide ELISA: antibody detection limit dilution 1:16000.

    Kommentare

    Flow Cytometry: Flow cytometric analysis of HeLa cells. Recommended concentration: 10ug/ml.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Minimize freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Kennah, Ringrose, Zhou, Esmailzadeh, Qian, Su, Zhou, Jiang: "Identification of tyrosine kinase, HCK, and tumor suppressor, BIN1, as potential mediators of AHI-1 oncogene in primary and transformed CTCL cells." in: Blood, Vol. 113, Issue 19, pp. 4646-55, (2009) (PubMed).

    Zhou, Zhao, Ringrose, DeGeer, Kennah, Lin, Sheng, Li, Turhan, Jiang: "AHI-1 interacts with BCR-ABL and modulates BCR-ABL transforming activity and imatinib response of CML stem/progenitor cells." in: The Journal of experimental medicine, Vol. 205, Issue 11, pp. 2657-71, (2008) (PubMed).

  • Target
    AHI1 (Abelson Helper Integration Site 1 (AHI1))
    Andere Bezeichnung
    AHI1 (AHI1 Produkte)
    Synonyme
    AHI1 antikoerper, AHI-1 antikoerper, JBTS3 antikoerper, ORF1 antikoerper, dJ71N10.1 antikoerper, 1700015F03Rik antikoerper, Ahi-1 antikoerper, D10Bwg0629e antikoerper, Abelson helper integration site 1 antikoerper, AHI1 antikoerper, ahi1 antikoerper, Ahi1 antikoerper
    Hintergrund
    AHI1, AHI-1, DKFZp686J1653, FLJ14023, FLJ20069, JBTS3, ORF1, dJ71N10.1, Abelson helper integration site, jouberin, Ahi-1 isoform I, OTTHUMP00000017263, OTTHUMP00000017264, OTTHUMP00000017265, contatins SH3 and WD40 domains, Abelson helper integration site 1
    Gen-ID
    54806
    NCBI Accession
    NP_060121, NP_001128304, NP_001337433
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