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KIF5B Antikörper (C-Term)

Verified KIF5B Reaktivität: Human WB, ELISA, IF Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN184774
  • Target Alle KIF5B Antikörper anzeigen
    KIF5B (Kinesin Family Member 5B (KIF5B))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 48
    • 27
    • 20
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 7
    • 1
    Ziege
    Klonalität
    • 44
    • 9
    Polyklonal
    Konjugat
    • 31
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIF5B Antikörper ist unkonjugiert
    Applikation
    • 40
    • 21
    • 16
    • 9
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Verwendungszweck
    Kinesin 1 / UKHC
    Sequenz
    QPVAVRGGGG KQV
    Kreuzreaktivität
    Rind (Kuh), Hund, Human, Maus, Ratte
    Aufreinigung
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Güteklasse
    Verified
    Immunogen
    Peptide with sequence C-QPVAVRGGGGKQV, from the C Terminus of the protein sequence according to NP_004512.1.
    Isotyp
    IgG
    Top Product
    Discover our top product KIF5B Primärantikörper
  • Applikationshinweise

    Western Blot: Approx 110 kDa band observed in lysates of the cell lines Jurkat and HeLa (calculated MW of 110 kDa according to NP_004512.1). Recommended concentration: 0.5-1.5 μg/mL. Primary incubation was 1 hour. This antibody has been successfully used in

    Peptide ELISA: antibody detection limit dilution 1:8000.

    Kommentare

    Additional validation: This antibody has been successfully used in the following paper: Sikorski et al. (2018) PMID: 30377371. Immunofluorescence:This antibody has been successfully used in IF on Human: Connell et al. (20

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Minimize freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Connell, Allison, Rodger, Pearson, Zlamalova, Reid: "ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic." in: Cellular and molecular life sciences : CMLS, Vol. 77, Issue 13, pp. 2641-2658, (2020) (PubMed).

    Robinson, Evans, Briggs, Ramalho, Hume: "Inefficient recruitment of kinesin-1 to melanosomes precludes it from facilitating their transport." in: Journal of cell science, Vol. 130, Issue 12, pp. 2056-2065, (2018) (PubMed).

    Yasuda, Clatterbuck-Soper, Jackrel, Shorter, Mili: "FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination." in: The Journal of cell biology, Vol. 216, Issue 4, pp. 1015-1034, (2017) (PubMed).

    Astanina, Jacob: "KIF5C, a kinesin motor involved in apical trafficking of MDCK cells." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 8, pp. 1331-42, (2010) (PubMed).

    Gupta, Palmer, Spence, Hudson, Stephens: "Kinesin-1 (uKHC/KIF5B) is required for bidirectional motility of ER exit sites and efficient ER-to-Golgi transport." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 11, pp. 1850-66, (2008) (PubMed).

  • Target
    KIF5B (Kinesin Family Member 5B (KIF5B))
    Andere Bezeichnung
    KIF5B (KIF5B Produkte)
    Synonyme
    KINH antikoerper, KNS antikoerper, KNS1 antikoerper, UKHC antikoerper, Khc antikoerper, AL022807 antikoerper, Khcs antikoerper, Kns1 antikoerper, Ukhc antikoerper, khc antikoerper, KIF5A antikoerper, kinesin family member 5B antikoerper, kinesin heavy chain antikoerper, kinesin-1 antikoerper, kinesin-1 heavy chain antikoerper, kinesin family member 5B S homeolog antikoerper, KIF5B antikoerper, LOC411769 antikoerper, cgd6_2790 antikoerper, kin-1 antikoerper, Tb927.1.1350 antikoerper, LACBIDRAFT_305999 antikoerper, Khc antikoerper, LOC100538629 antikoerper, Kif5b antikoerper, kif5b.S antikoerper
    Hintergrund
    KIF5B, UKHC, kinesin 1 (110-120kD), kinesin family member 5B, KNS, KINH, KNS1, U-KHC, kinesin heavy chain
    Gen-ID
    3799
    NCBI Accession
    NP_004512
    Pathways
    Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
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