STAT-Induced STAT Inhibitor 3 (SOCS3) Antikörper

Antigen: STAT-Induced STAT Inhibitor 3 (SOCS3)

Synonyme: CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3, MGC71791, Cis3, Ef10, Ssi3, EF-10

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN184566

Produktbeschreibung

Weitere Bezeichnung: SOCS3

Gen-ID: 9021, 12702 (mouse), 89829 (rat)

Immunogen: C-PIREFLDQYDAPL

Format: Affinity-purified

Beschreibung: All names and symbols: SOCS3, CIS3, Cish3, SSI-3, SOCS-3, suppressor of cytokine signaling 3, STAT induced STAT inhibitor 3, cytokine-induced SH2 protein 3. Official Symbol: SOCS3. RefSeq number(s): NP_003946.3. Gene ontology terms: intracellular signaling cascade, regulation of cell growth

Spezifität: Human, Mouse, Rat, Dog, Pig 225 aa

Anwendungen

Applikationshinweise: Western blot: Approx 24kDa band seen in MOLT-4 lysate. Recommended for use at 4-6µg/ml.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Forschungsgebiet: Krebs, Hämopoetische Vorläufer, Angeborene Immunität, Zytokine, Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN184566 staining (5µg/ml) of MOLT-4 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publikationen

Publikationen: Roberts, Robb, Rakar et al.: "Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 9324-9, 2001 (PubMed).