YARS Antikörper (C-Term)

Produktnummer ABIN183962

Produktdetails anti-YARS Antikörper

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Ziege, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QVEPLDPPAG SAPGEHVFVK GYEKGQPDEE LKPKKKVFEK LQADFKISEE

Homologie: Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against YARS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human YARS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 528 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu YARS

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Andere Bezeichnung: YARS (Yars Produkte)

Synonyme: CMTDIC antikoerper, TYRRS antikoerper, YRS antikoerper, YTS antikoerper, AL024047 antikoerper, AU018965 antikoerper, cb204 antikoerper, wu:fk52b08 antikoerper, YARS antikoerper, cmtdic antikoerper, tyrrs antikoerper, yrs antikoerper, yts antikoerper, CG4561 antikoerper, Dmel\\CG4561 antikoerper, TyrRS antikoerper, anon-EST:Posey261 antikoerper, dYARS antikoerper, GB10789 antikoerper, tyrosyl-tRNA synthetase antikoerper, tyrosyl-tRNA synthetase L homeolog antikoerper, tyrosyl-tRNA synthetase, putative antikoerper, tyrosine--tRNA ligase antikoerper, Tyrosyl-tRNA synthetase antikoerper, tyrosine--tRNA ligase, cytoplasmic antikoerper, YARS antikoerper, Yars antikoerper, yars antikoerper, yars.L antikoerper, MAL8P1.125 antikoerper, MEFER_RS04475 antikoerper, TyrRS antikoerper, LOC413909 antikoerper, LOC100163888 antikoerper, LOC100282315 antikoerper

Hintergrund: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Alias Symbols: YRS, YTS, TYRRS, CMTDIC
Protein Interaction Partner: UBC, SARNP, NRD1, HSPA8, VCAM1, ITGA4, FN1, METTL16, XRCC5, DYNC1H1, CDK2, ELANE, EIF1B, SAP18, EIF6, ARF6,
Protein Size: 528

Molekulargewicht: 58 kDa

Gen-ID: 8565

NCBI Accession: NM_003680, NP_003671

UniProt: P54577