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SNRNP70 Antikörper (N-Term)

SNRNP70 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN183913
  • Target Alle SNRNP70 Antikörper anzeigen
    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 23
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Pferd
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SNRNP70 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 14
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SNRP70
    Top Product
    Discover our top product SNRNP70 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 437 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Mueller, Hertel, Cambi: "G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4059-71, (2011) (PubMed).

    Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

  • Target
    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
    Andere Bezeichnung
    SNRP70 (SNRNP70 Produkte)
    Synonyme
    rnpu1z antikoerper, rpu1 antikoerper, snrp70 antikoerper, u170k antikoerper, u1ap antikoerper, u1rnp antikoerper, SNRP70 antikoerper, wu:fc20b04 antikoerper, zgc:136450 antikoerper, 2700022N21Rik antikoerper, 3200002N22Rik antikoerper, 70kDa antikoerper, AI325098 antikoerper, R74807 antikoerper, Rnulp70 antikoerper, Snrp70 antikoerper, Srnp70 antikoerper, U1-70 antikoerper, U1-70K antikoerper, RNPU1Z antikoerper, RPU1 antikoerper, Snp1 antikoerper, U170K antikoerper, U1AP antikoerper, U1RNP antikoerper, small nuclear ribonucleoprotein, U1 70kDa subunit antikoerper, small nuclear ribonucleoprotein U1 subunit 70 antikoerper, small nuclear ribonucleoprotein 70 (U1) antikoerper, small nuclear ribonucleoprotein, U1 70kDa subunit L homeolog antikoerper, snrnp70 antikoerper, SNRNP70 antikoerper, Snrnp70 antikoerper, snrnp70.L antikoerper
    Hintergrund
    SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
    Alias Symbols: RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K
    Protein Interaction Partner: IL32, UBC, NEDD8, LIN28A, EZH2, SUZ12, EED, RNF2, rev, WBP4, SRPK2, SRPK1, MYC, SRPK3, HDAC2, PAN2, SMURF2, PRPF40A, CDKL3, RNF11, PRKD2, SKIL, RELA, RASGRF1, SMAD9, SMAD5, SMAD4, SMAD3, SMAD2, CHERP, PRMT5, UBL4A, VCAM1, SMAD1, ITGA4, IL7R, IFIT3, IFIT1,
    Protein Size: 437
    Molekulargewicht
    52 kDa
    Gen-ID
    6625
    NCBI Accession
    NM_003089, NP_003080
    UniProt
    P08621
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