CNOT7 Antikörper (N-Term)

Produktnummer ABIN183752

Produktdetails anti-CNOT7 Antikörper

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Kaninchen, Ziege, Meerschweinchen, Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: TEFPGVVARP IGEFRSNADY QYQLLRCNVD LLKIIQLGLT FMNEQGEYPP

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CNOT7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNOT7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 262 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CNOT7 Antikörper (ABIN183752)

Maragozidis, Karangeli, Labrou, Dimoulou, Papaspyrou, Salataj, Pournaras, Matsouka, Gourgoulianis, Balatsos: "Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker." in: Acta haematologica, Vol. 128, Issue 1, pp. 39-46, (2012) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu CNOT7

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Andere Bezeichnung: CNOT7 (CNOT7 Produkte)

Synonyme: CNOT7 antikoerper, CAF1 antikoerper, fd59c07 antikoerper, fj07d05 antikoerper, wu:fd59c07 antikoerper, wu:fj07d05 antikoerper, zgc:153168 antikoerper, caf1 antikoerper, Caf1a antikoerper, hCAF-1 antikoerper, AU022737 antikoerper, CAF-1 antikoerper, Caf1 antikoerper, Pop2 antikoerper, CCR4-NOT transcription complex subunit 7 antikoerper, ccr4-not transcription complex, subunit 7 antikoerper, CCR4-NOT transcription complex, subunit 7 antikoerper, ccr4-not transcription complex, subunit 7, putative antikoerper, CCR4-NOT transcription complex subunit 7 S homeolog antikoerper, CNOT7 antikoerper, CNL04550 antikoerper, GL50803_10606 antikoerper, GL50803_8209 antikoerper, CGB_D2510C antikoerper, cnot7 antikoerper, cnot7.S antikoerper, Cnot7 antikoerper

Hintergrund: CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: CAF1, hCAF-1
Protein Interaction Partner: FBXW11, TOB2, BTG2, FOXC2, UBC, BAG3, CNOT6, AGO2, AGO1, EPAS1, APP, ELAVL1, BTG1, Cnot3, HOXD4, IKBKG, BTG3, TOB1, CDK6, CDK4, CDK2, CDK1, PABPC1,
Protein Size: 262

Molekulargewicht: 30 kDa

Gen-ID: 29883

NCBI Accession: NM_013354, NP_037486

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization