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IRF5 Antikörper (N-Term)

IRF5 Reaktivität: Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN183457
  • Target Alle IRF5 Antikörper anzeigen
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Bindungsspezifität
    • 9
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 72
    • 48
    • 22
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    Maus, Ratte
    Wirt
    • 73
    • 10
    • 1
    • 1
    Kaninchen
    Klonalität
    • 65
    • 20
    Polyklonal
    Konjugat
    • 53
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser IRF5 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 30
    • 12
    • 11
    • 10
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    CSNGPAPTES QPTDDYVLGE EEEEEEEELQ RMLPGLSITE PALPGPPNAP
    Homologie
    Mouse: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against IRF5. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of mouse IRF5
    Top Product
    Discover our top product IRF5 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 497 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Takaoka, Yanai, Kondo, Duncan, Negishi, Mizutani, Kano, Honda, Ohba, Mak, Taniguchi: "Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." in: Nature, Vol. 434, Issue 7030, pp. 243-9, (2005) (PubMed).

  • Target
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Andere Bezeichnung
    IRF5 (IRF5 Produkte)
    Synonyme
    IRF5 antikoerper, irf5 antikoerper, SLEB10 antikoerper, AW491843 antikoerper, mirf5 antikoerper, im:7155364 antikoerper, zgc:76986 antikoerper, interferon regulatory factor 5 antikoerper, interferon regulatory factor 5 L homeolog antikoerper, IRF5 antikoerper, irf5 antikoerper, Irf5 antikoerper, irf5.L antikoerper
    Hintergrund
    The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
    Alias Symbols: mirf5, AW491843
    Protein Interaction Partner: Ubc, Traf6, Irak1, Zfp764, Myd88, Il12b,
    Protein Size: 497
    Molekulargewicht
    55 kDa
    Gen-ID
    27056
    NCBI Accession
    NM_012057, NP_036187
    UniProt
    P56477
    Pathways
    TLR Signalweg, Autophagie
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