Prohibitin Antikörper (C-Term)

Produktnummer ABIN182681

Produktdetails anti-Prohibitin Antikörper

Target: Prohibitin (PHB)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prohibitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AEQQKKAAII SAEGDSKAAE LIANSLATAG DGLIELRKLE AAEDIAYQLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PHB. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 272 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Prohibitin

Target: Prohibitin (PHB)

Andere Bezeichnung: PHB (PHB Produkte)

Synonyme: phb1 antikoerper, MGC75944 antikoerper, PHB antikoerper, Phb antikoerper, ACYPI000080 antikoerper, phb antikoerper, PHB1 antikoerper, Bap32 antikoerper, sr:nyz128 antikoerper, wu:fa18f07 antikoerper, wu:fb09f05 antikoerper, prohibitin1 antikoerper, xphb1 antikoerper, prohibitin antikoerper, prohibitin-2 antikoerper, prohibitin L homeolog antikoerper, PHB antikoerper, phb antikoerper, LOC484431 antikoerper, LOC5576054 antikoerper, Phb antikoerper, phb.L antikoerper

Hintergrund: Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Alias Symbols: PHB1
Protein Interaction Partner: FUS, HUWE1, SUMO2, SPRTN, STAU1, MDM2, SUZ12, EED, RNF2, PARP1, NAP1L1, COX6C, LONRF3, FBXO6, ADRB2, HDAC5, RAF1, KRAS, RAPH1, IPO11, SMG5, YWHAZ, YWHAB, VDAC2, RPS4X, RPL7, PRKCD, PLEC, NPM1, LMNA, IGHG1, HSP90AB1, GTF3C1, DBN1, COL9A2, CAPZA1, SLC25A5,
Protein Size: 272

Molekulargewicht: 30 kDa

Gen-ID: 5245

NCBI Accession: NM_002634, NP_002625

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling